Tier 2 — strong

The effect of berberine on obesity indices: a systematic review and meta-analysis

Elahi Vahed I, Shahir-Roudi E, Nojumi S, Golmohammadi S, Moradi Shahrebabak M, Sharafi Tafreshi Moghadam N, Bagheryan AS, Moftakhar M, Shamsipour F, Jafari M, Soltaninejad H, Rahmanian M
International journal of obesity (2005) 2026 50(1):53-73

Bibliography

PubMed
PMID 41310257
Funding
Funding was not established from the accessible source; this is not a declaration of no funding.
Competing interests
A complete competing-interest declaration was not available in the accessible source; no absence of conflicts is inferred.

Study snapshot

DesignSystematic review and meta-analysis
ModelPublished human studies
Sample23 articles
InterventionEvidence synthesis; interventions and comparators vary across included studies
DurationNo new treatment; included-study durations vary
EndpointsPooled clinical or metabolic outcomes; Risk of bias and heterogeneity; Adverse-event reporting

What the study showed, in plain terms

The updated synthesis estimated a small mean weight reduction, about 0.88 kg, with lower BMI and waist circumference but no clear waist-to-hip ratio effect.

Key findings

  • The updated synthesis estimated a small mean weight reduction, about 0.88 kg, with lower BMI and waist circumference but no clear waist-to-hip ratio effect.

What this study can and cannot tell us

Trial quality and preparation characterization vary. The abstract mislabels waist units, so its waist estimate should not be copied without checking the source tables.

Source detail: indexed abstract and bibliographic record; unavailable methods or disclosures are identified rather than assumed.

Citation network

Articles citing this research paper

12 articles

Biohack Blueprint analyses that reference this study in their evidence base.

Editorial review

Reviewed by the Biohack Blueprint research team

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