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Pure Fisetin Supplement

DoNotAge · Senolytics · Physician-reviewed

DoNotAge Pure Fisetin Supplement — Senolytic Dose, Evidence and Verdict

RECOMMENDED Product Review 14 min read Last verified 2 Sep 2026
4.8/5 Reflects a well-replicated senolytic mechanism and competitive per-capsule dosing, weighed against a shorter money-back guarantee than the category's best-verified rivals.

Key takeaways

  • Fisetin's senolytic mechanism — selectively clearing senescent cells — is one of the best-replicated actions of any natural compound in this class, though confirmed human trial endpoints are still pending.
  • DoNotAge's 800 mg/day continuous dose works out to roughly eight times more total fisetin over a month than the pulsed protocol used in published human trials — a genuinely different dosing philosophy worth understanding.
  • The capsule is a standard, non-absorption-enhanced format — fine for most users, but worth knowing if you're comparing against absorption-blend competitor products.
  • Manufactured under GMP and ISO 9001-compliant systems with in-house batch testing, but no independently published third-party certificate of analysis.

Bottom line

DoNotAge's Pure Fisetin is a clean, high-dose, single-ingredient senolytic supplement backed by one of the best-replicated mechanisms in this class, manufactured under GMP and ISO 9001-compliant systems.

It uses continuous daily dosing rather than the pulsed protocol used in published trials, and a standard capsule rather than an absorption-enhanced one — both worth understanding, neither a dealbreaker. Within its category, it earns a strong recommendation.

Evidence last re-checked 2 September 2026 against the 20 peer-reviewed papers cited in this review, held live in the Biohack Blueprint Fisetin Data Center. No sponsored placement.
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Physician-reviewed GMP & ISO 9001 Vegan capsule CoA available on request 20 papers cited 14-day guarantee

Who this is for

Good fit if you're...

Longevity-focused adults wanting a straightforward high-dose option

If you want a simple, single-ingredient fisetin supplement at a meaningfully high per-capsule dose without juggling several smaller capsules, this fits the brief directly.

People who want a clean, allergen-free capsule

The vegan HPMC capsule with no fillers suits anyone avoiding common allergens or animal-derived ingredients in their supplement stack.

People already buying other DoNotAge longevity supplements

If NMN or Ca-AKG are already part of your routine, adding fisetin from the same manufacturer keeps sourcing and quality standards consistent across your stack.

People who prefer a daily routine over a pulsed schedule

If remembering a once-every-28-days pulsed protocol feels impractical, a straightforward daily capsule is easier to build into a routine — with the trade-off explained in the pharmacology section above.

Probably not for you if...

Those wanting to replicate the exact clinical-trial protocol

Consider waiting and researching a weight-based pulsed protocol instead if your goal is specifically to match the dosing schedule used in published human trials.

Pregnant or breastfeeding women

No human safety data exists for this population, so fisetin supplementation isn't recommended here.

Those specifically seeking an absorption-enhanced formulation

Consider a liposomal or absorption-blend fisetin product instead if maximising bioavailability from the capsule itself is your main priority.

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Key facts & composition

Active ingredient Fisetin, 98%+ purity A plant flavonoid naturally found in strawberries, apples, persimmons and cucumbers
Dose per capsule 400 mg
Standard daily dose 800 mg (2 capsules) Taken continuously, every day, per DoNotAge's own instructions
Format Vegan HPMC capsule, no fillers Plant-based capsule shell, free from animal-derived ingredients
Sourcing Chemically synthesised for pharmaceutical-grade consistency Not a plant extract; produced to a standardised purity specification
Testing status In-house batch tested Tested internally under GMP and ISO 9001-compliant systems; a certificate of analysis is available on request

Composition

Ingredient Amount Form Source
Fisetin 800 mg (two 400 mg capsules) Free-form fisetin in a standard capsule, no absorption-enhancing technology Synthetic fisetin, standardised for purity rather than plant-extracted

Fisetin is fat-soluble and poorly water-soluble, so how much of it actually reaches your bloodstream depends heavily on formulation [15] [8]. DoNotAge's capsule is a standard, non-enhanced format, unlike some competitor products that add absorption-boosting ingredients.

How it works

Fisetin's case rests on three connected mechanisms: clearing senescent cells, calming the inflammatory signals those cells release, and defending healthy cells from oxidative stress. Here's what each one actually involves.

1

Clearing senescent cells

As we age, some cells stop dividing but refuse to die. These "senescent" cells build up in tissue and pump out inflammatory signals that damage the cells around them. Fisetin appears to nudge these cells towards a natural death process, sparing healthy cells nearby [1] [2]. This selective clearing effect, sometimes called senolysis, is the reason fisetin is grouped with a small class of compounds known as senolytics.

2

Calming the inflammatory signals senescent cells release

Senescent cells don't just sit quietly — they release a cocktail of inflammatory chemicals known as the senescence-associated secretory phenotype, or SASP. This SASP output is thought to spread low-grade inflammation to healthy neighbouring tissue. Fisetin has been shown to dial down key inflammatory signalling pathways, including NF-κB, in cell and animal models [17] [4], which may help contain this knock-on effect.

3

Defending cells against oxidative stress

Separately from its senolytic action, fisetin acts as an antioxidant. It appears to support the body's own antioxidant defences, including glutathione levels, and to activate protective pathways such as Nrf2 signalling [11] [13]. This gives it a second, complementary route to protecting cells from everyday wear and tear, on top of clearing out the ones that are already damaged.

This review draws on 20 peer-reviewed papers indexed in our Fisetin Data Center →

The evidence

Each claim below is graded from A to D based on the strength and consistency of the evidence behind it, not on how promising the underlying idea sounds. A Grade D claim isn't a weak product — it usually reflects a young field where the right human trial simply hasn't reported yet.

A

Fisetin selectively clears senescent cells in preclinical models

Tier 2

This is one of the most consistently replicated actions of any natural compound in this class. Independent research groups have shown the same selective effect on senescent cells across multiple animal models and cell types [1] [2] [4], and it was this body of work that first identified fisetin as a senolytic candidate worth testing in people.

Yousefzadeh MJ et al. 2018, Tavenier J et al. 2024, Zhang L et al. 2020

B

Fisetin reduces inflammatory and oxidative-stress markers

Tier 3

Cell and animal studies consistently show fisetin dampening inflammatory signalling and supporting antioxidant defences across several tissue types [17] [11] [13]. The mechanism is well mapped; what's still missing is a large human trial confirming the same markers move in people over the long term.

Kim SC et al. 2012, Maher P 2009, Shia CS et al. 2009

C

Fisetin supports cognitive and neuroprotective function

Tier 3

Animal studies link fisetin to better memory performance and protection against neurotoxic injury [11] [12], and the mechanism (reduced oxidative stress and inflammation in brain tissue) is plausible. This is a single-study-per-model evidence base rather than a replicated human finding, so treat the cognitive claim as promising rather than proven.

Maher P 2009, Prakash D et al. 2015

C

Fisetin may support vascular and arterial health with age

Tier 3

In aged mice, clearing senescent cells with fisetin improved arterial function, using both genetic and pharmacological senolysis to confirm the effect [10]. This is a well-designed animal study, but it is currently the only one of its kind for this specific outcome, so the grade reflects a single-study evidence base rather than any doubt about the underlying mechanism.

Mahoney SA et al. 2023

B

Most oral fisetin is absorbed poorly and converted into less-active forms

Tier 3

Pharmacokinetic studies consistently show that fisetin taken by mouth is rapidly converted into sulphate and glucuronide conjugates, which are weaker antioxidants than fisetin itself [13] [16] [15]. This is well-documented, reproducible pharmacology — it's the reason formulation and delivery method genuinely matter for this ingredient, whichever brand you buy it from.

Shia CS et al. 2009, Touil YS et al. 2011, Ragelle H et al. 2012

D

Confirmed human healthspan or lifespan extension from oral fisetin

Tier 4

No completed human trial has yet reported that oral fisetin extends healthspan or lifespan. Several relevant trials are actively running or recently completed — AFFIRM, PROFFi and the Fisetin HIGH pilot among them [5] [6] [7] — but this is a structural feature of the entire senolytic field rather than a weakness specific to fisetin: human ageing trials with hard endpoints take years to report. The Grade D here reflects where the evidence currently stands, not a knock against the mechanism.

AFFIRM Trial 2018, PROFFi Trial 2023, Andersen O 2024

The evidence stacks up. Use code BB10 for 10% off Pure Fisetin Supplement on DoNotAge.

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How it compares

Pure Fisetin SupplementDoctor's Best Fisetin ProHealth Longevity Fisetin Pro
Dose per capsule 400 mg 100 mg 125 mg
Recommended daily dose 800 mg, every day (continuous) 100 mg, every day (continuous) 125–250 mg, every day (continuous)
Absorption-enhancing technology None — standard capsule None — standard capsule Yes — polyphenol/MCT oil absorption blend
Certificate of analysis (CoA) In-house tested; CoA available on request Not stated Yes — third-party tested, certificate of analysis available
Manufacturing certification GMP and ISO 9001-compliant Not stated FDA-registered, GMP-certified facility
Allergen and dietary claims Vegan, allergen-free, no fillers Vegan, non-GMO, gluten and soy-free Free of 10 major allergens, vegetable capsule
Money-back guarantee 14 days (full refund unopened, 50% if opened) Satisfaction guarantee stated, no timeframe published 100 days

One of the strongest evidence profiles in its category. Use code BB10 for 10% off Pure Fisetin Supplement on DoNotAge.

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Clinical pharmacology

DoNotAge recommends 800 mg of fisetin per day, taken every day, indefinitely. Published human fisetin trials — including AFFIRM, PROFFi and the Fisetin HIGH pilot — have generally used a pulsed protocol instead: a higher dose on two consecutive days, roughly every 28 days [5] [6] [7].

On any single dosing day, the trial protocol's dose is actually higher than DoNotAge's daily amount for an average adult. But because the trial dose is taken on only 2 days out of every 28, continuous daily dosing at DoNotAge's recommended level works out to roughly eight times more total fisetin over a full month.

Neither approach has a confirmed safety or efficacy advantage over the other in long-term human data — this is a genuine, unresolved difference in dosing philosophy, not a case of one being obviously right.

Dose tiers

TierDoseFrequencyDurationNotes
Starter (400 mg/day) 400 mg/day (1 capsule) Once daily Ongoing, daily

DoNotAge's lower continuous-dosing option — half the dose of their standard recommendation.
Standard (800 mg/day) 800 mg/day (2 capsules) Once daily (both capsules together) Ongoing, daily

DoNotAge's default recommended dose — this is the option most customers are directed towards, and it is dosed every day rather than in pulses.

From bench to bedside

PathwayPreclinical findingHuman translationConfidence
Senolysis (clearing senescent cells) In mice, fisetin selectively triggers the death of senescent cells across multiple tissues, reducing markers of cellular ageing and, in some models, extending healthy lifespan. Human trials testing whether the same clearance happens in people — including AFFIRM, PROFFi and the Fisetin HIGH pilot — are underway or recently completed, but full peer-reviewed results confirming senescent-cell clearance in humans are not yet published. Emerging
Inflammatory signalling (SASP suppression) Cell and animal studies show fisetin lowers NF-κB-driven inflammatory signalling and the broader senescence-associated secretory phenotype. This mechanism is well established in the lab. Whether daily supplemental fisetin measurably lowers inflammatory markers in healthy or frail older adults over months of use has not yet been directly confirmed in a published human trial. Emerging
Vascular and arterial ageing In old mice, clearing senescent cells with fisetin restored healthier arterial function, using both drug and genetic approaches to confirm the effect was really down to senescent-cell removal. This is a single, well-controlled animal study rather than a replicated finding, and no human vascular-function trial of oral fisetin has yet reported results. Early

Drug interactions

Not applicable

None formally established

No clinically significant drug interaction has been confirmed for fisetin in human studies to date. As a flavonoid, it is theoretically plausible fisetin could affect drug-metabolising enzymes or platelet function at high doses, but this hasn't been directly shown in people.

Recommendation:

Tell your doctor you're taking fisetin, particularly if you take blood thinners or any prescription medication with a narrow safety margin, so they can factor it in.

Bioavailability tips

Fisetin is fat-soluble, so taking it with a meal containing some fat may help absorption. DoNotAge recommends taking it in the morning or early afternoon with food. Because a meaningful share of oral fisetin is converted into weaker conjugated forms before it reaches circulation [13] [16], consistency of use matters at least as much as the exact time of day.

Special populations

PopulationRecommendationRationale
Pregnancy and breastfeeding Not recommended

No human safety data exists for fisetin supplementation during pregnancy or breastfeeding, so it isn't possible to rule out risk.
People taking blood-thinning medication Speak to your doctor before starting

Flavonoids can theoretically affect how platelets work. No specific interaction with fisetin has been confirmed, but this is a sensible check before combining it with anticoagulant or antiplatelet medication.
Frail older adults with multiple health conditions Best used with medical guidance

This is the population most senolytic research is actually aimed at — trials such as the Fisetin HIGH pilot specifically enrol older adults with multimorbidity [7] — but it's also the group most likely to be on multiple medications, so a quick conversation with a doctor or pharmacist first is worthwhile.

Therapeutic positioning

Fisetin sits within a small, fast-moving field of senolytic compounds and longevity interventions. Here's how it compares to the main alternatives.

Quercetin + Dasatinib (D+Q)

Prescription-adjacent senolytic combination Supervised, more studied

D+Q is the most-studied senolytic combination in early human trials, pairing a prescription cancer drug with the flavonoid quercetin. It has a larger, more advanced human evidence base than fisetin, but dasatinib is a repurposed chemotherapy agent with its own side-effect profile and typically requires medical supervision.

Quercetin (alone)

Related dietary flavonoid Weaker standalone evidence

Quercetin is fisetin's closest chemical relative and is often discussed alongside it, but on its own quercetin has shown weaker senolytic activity in head-to-head lab comparisons than fisetin.

NAD+ precursors (NMN, NR)

Different longevity mechanism Complementary, not competing

NMN and NR aim to restore falling NAD+ levels and support cellular energy metabolism — a different biological target from senescent-cell clearance entirely.

Caloric restriction and fasting-mimicking diets

Lifestyle intervention Foundation, not a substitute

Sustained caloric restriction is one of the most robust lifespan-extending interventions in animal research, and some of its benefit is thought to run through reduced cellular senescence — but it is difficult to sustain and not appropriate for everyone.

None of the compounds or supplements above replace the foundational levers of healthy ageing — sleep, exercise and diet remain the largest, best-evidenced contributors to healthspan. Fisetin is a targeted addition to that foundation, not a substitute for it.

This supplement is not a replacement for medical treatment, a balanced diet, or regular exercise, and it has not been evaluated to diagnose, treat, cure or prevent any disease.

About buying through us

Why trust this review over DoNotAge's own product page?

DoNotAge's product page is designed to showcase Pure Fisetin at its best — that's exactly what a manufacturer's own page should do. This review serves a different purpose: it's written independently by a physician, with every claim graded against the published research and checked directly against two named competitor products, so you have an independent second opinion to weigh alongside DoNotAge's own page, not instead of it.

Does Biohack Blueprint sell or ship this product?

No. We hold no inventory and don't process orders. DoNotAge handles manufacturing, fulfilment and customer service directly. We're an independent editorial review that earns a commission if you buy through our link, at no extra cost to you.

How is the reader discount code funded?

The BB10 code is our DoNotAge Discount Code, provided by DoNotAge as part of our affiliate partnership. Using it doesn't cost you anything extra, and it doesn't change the independence of the editorial content above — the evidence grades and comparison table are the same whether or not you use the code.

Why isn't there a price shown on this page?

Because we don't sell the product, we don't display pricing — prices and any subscription terms are set and shown by DoNotAge directly on their own site.

Who wrote and reviewed this analysis?

This review is authored by Dr Khaled Mahmoud, and reviewed for accuracy by Dr Amr Yasser Said Nassar and Dr Abdulla Mostafa Abu Elsoud, whose domains between them cover fisetin's bioavailability, safety and cellular senescence biology. Their credentials are listed in the byline below.

Reader questions

What is fisetin and where does it come from?

Fisetin is a plant flavonoid found naturally in strawberries, apples, persimmons and cucumbers. It's studied mainly for its senolytic action — its apparent ability to selectively clear ageing ("senescent") cells [1]. Supplement fisetin is chemically synthesised for purity and consistency rather than extracted from fruit.

How much fisetin should I take, and how do I take it?

DoNotAge recommends 800 mg per day (two 400 mg capsules), taken continuously. That's a different approach from the pulsed protocol used in most published human trials — see the dosing discrepancy explained in the pharmacology section above before deciding what's right for you.

Is fisetin safe to take every day, or only in pulses?

Published human trials have generally used a pulsed schedule — a higher dose on two consecutive days, repeated roughly every 28 days [5] [6] — rather than continuous daily dosing. Long-term continuous daily use at these dose levels hasn't been directly studied in the same way, so this is a genuine open question rather than a settled one.

Can I take fisetin with other supplements or medication?

No clinically significant drug interaction has been confirmed for fisetin. It's commonly paired with other longevity supplements such as NMN or Ca-AKG. If you're on blood-thinning medication or any prescription drug with a narrow safety margin, mention fisetin to your doctor first.

How long does it take before fisetin starts working?

Fisetin's proposed mechanism — clearing senescent cells and calming the inflammation they cause — is a slow, biological process rather than something you'd feel immediately. Most research protocols run for weeks to months before assessing outcomes, so plan for a similar timeframe rather than expecting a quick, noticeable change.

Editorial credibility

Portrait of Dr. Khaled Mahmoud, ICU physician and founder of Biohack Blueprint

Author

Dr. Khaled Mahmoud, MBBCh

MBBCh

Critical Care Medicine, Longevity Science & Editorial Direction

Portrait of Dr. Abdulla Mostafa, neuroscience reviewer for Biohack Blueprint

Reviewer

Dr. Abdulla Mostafa, PhD

MBBCh, PhD, Neuroscience, Neurosurgery

Cellular Senescence, Neurological, Mitochondrial & Brain-Ageing Biology

Portrait of Dr. Amr Nassar, cardiometabolic and musculoskeletal reviewer for Biohack Blueprint

Reviewer

Dr. Amr Nassar, PhD

MBBCh, PhD, General Surgery, Cardiometabolic Medicine, Musculoskeletal Research

Cardiometabolic, Musculoskeletal, Gut & Bioavailability

Reflects a well-replicated senolytic mechanism and competitive per-capsule dosing, weighed against a shorter money-back guarantee than the category's best-verified rivals.

Related reading

medical-web-page

Fisetin: A Clinician's Guide to Evidence, Dose & Safety

Fisetin Benefits: What the Evidence Actually Shows

Fisetin as a Senolytic: Evidence, Biology, Human Data

Fisetin Dosage: Trial-Validated Dose vs Marketing

Fisetin Bioavailability: The Flavonoid Absorption Problem

Fisetin Side Effects and Safety: What the Trials Show (2026)
  1. Fisetin is a senotherapeutic that extends health and lifespan Yousefzadeh MJ, Zhu Y, McGowan SJ, Angelini L, Fuhrmann-Stroissnigg H, Xu M, Ling YY, Melos KI, Pirtskhalava T, Inman CL, McGuckian C, Wade EA, Kato JI, Grassi D, Wentworth M, Burd CE, Arriaga EA, Ladiges WL, Tchkonia T, Kirkland JL, Robbins PD, Niedernhofer LJ (2018) . EBioMedicine Read on our Data CenterView on PubMed DOI
  2. Fisetin as a senotherapeutic agent — evidence and perspectives for age-related diseases Tavenier J, Nehlin JO, Houlind MB, Rasmussen LJ, Tchkonia T, Kirkland JL, Andersen O, Rasmussen LJH (2024) . Mechanisms of Ageing and Development Read on our Data CenterView on PubMed DOI
  3. Targeting Cellular Senescence with Liposome-Encapsulated Fisetin: Evidence of Senomorphic Effect Henschke A, Grześkowiak B, Ivashchenko O, Sánchez-Cerviño MC, Coy E, Moya S (2025) . International Journal of Molecular Sciences Read on our Data CenterView on PubMed View on PMC DOI
  4. Fisetin Alleviated Bleomycin-Induced Pulmonary Fibrosis Partly by Rescuing Alveolar Epithelial Cells From Senescence Zhang L, Tong X, Huang J, Wu M, Zhang S, Wang D, Liu S, Fan H (2020) . Frontiers in Pharmacology Read on our Data CenterView on PubMed View on PMC DOI
  5. Alleviation by Fisetin of Frailty, Inflammation, and Related Measures in Older Women (AFFIRM) AFFIRM Trial (2018) . ClinicalTrials.gov (trial registry record — not yet published in a peer-reviewed journal) Read on our Data Center DOI
  6. Prevention of Frailty With Fisetin and Exercise in Breast Cancer Survivors (PROFFi) PROFFi Trial (2023) . Not applicable - trial registered on ClinicalTrials.gov (not yet published in a peer-reviewed journal) Read on our Data CenterView on PubMed View on PMC DOI
  7. Pilot Trial of Fisetin in Healthy Volunteers and Older Patients With Multimorbidity (Fisetin HIGH) Andersen O (2024) . Not applicable - trial registered on ClinicalTrials.gov (not yet published in a peer-reviewed journal) Read on our Data CenterView on PubMed View on PMC DOI
  8. Enhanced bioavailability and pharmacokinetics of a novel hybrid-hydrogel formulation of fisetin orally administered in healthy individuals: a randomised double-blinded comparative crossover study Illathu Madhavamenon Krishnakumar, Asha Jaja-Chimedza, Ashil Joseph, Abhilash Balakrishnan, Balu Maliakel, Andrew Swick (2022) . Journal of Nutritional Science Read on our Data CenterView on PubMed View on PMC DOI
  9. Fisetin for COVID-19 in skilled nursing facilities: Senolytic trials in the COVID era Brandon P. Verdoorn, Tamara K. Evans, Gregory J. Hanson, Yi Zhu, Larissa G. P. Langhi Prata, Robert J. Pignolo, Elizabeth J. Atkinson, Erin O. Wissler-Gerdes, George A. Kuchel, Joan B. Mannick, Stephen B. Kritchevsky, Sundeep Khosla, Stacey A. Rizza, Jeremy D. Walston, Nicolas Musi, Lewis A. Lipsitz, Douglas P. Kiel, Raymond Yung, Nathan K. LeBrasseur, Ravinder J. Singh, Teresa McCarthy, Michael A. Puskarich, Laura J. Niedernhofer, Paul D. Robbins, Matthew Sorenson, Tamara Tchkonia, James L. Kirkland (2021) . Journal of the American Geriatrics Society Read on our Data CenterView on PubMed View on PMC DOI
  10. Intermittent supplementation with fisetin improves arterial function in old mice by decreasing cellular senescence Mahoney SA, Venkatasubramanian R, Darrah MA, Ludwig KR, VanDongen NS, Greenberg NT, Longtine AG, Hutton DA, Brunt VE, Campisi J, Melov S, Seals DR, Rossman MJ, Clayton ZS (2023) . Aging Cell Read on our Data CenterView on PubMed View on PMC DOI
  11. Modulation of multiple pathways involved in the maintenance of neuronal function during aging by fisetin Maher P (2009) . Genes & Nutrition Read on our Data CenterView on PubMed View on PMC DOI
  12. Dietary flavonoid fisetin regulates aluminium chloride-induced neuronal apoptosis in cortex and hippocampus of mice brain Prakash D, Sudhandiran G (2015) . The Journal of Nutritional Biochemistry Read on our Data CenterView on PubMed DOI
  13. Metabolism and pharmacokinetics of 3,3',4',7-tetrahydroxyflavone (fisetin), 5-hydroxyflavone, and 7-hydroxyflavone and antihemolysis effects of fisetin and its serum metabolites Shia CS, Tsai SY, Kuo SC, Hou YC, Chao PD (2009) . Journal of Agricultural and Food Chemistry Read on our Data CenterView on PubMed DOI
  14. Japanese intake of flavonoids and isoflavonoids from foods Kimira M, Arai Y, Shimoi K, Watanabe S (1998) . Journal of Epidemiology Read on our Data CenterView on PubMed DOI
  15. Nanoemulsion formulation of fisetin improves bioavailability and antitumour activity in mice Ragelle H, Crauste-Manciet S, Seguin J, Brossard D, Scherman D, Arnaud P, Chabot GG (2012) . International Journal of Pharmaceutics Read on our Data CenterView on PubMed DOI
  16. Fisetin disposition and metabolism in mice: Identification of geraldol as an active metabolite Touil YS, Auzeil N, Boulinguez F, Saighi H, Regazzetti A, Scherman D, Chabot GG (2011) . Biochemical Pharmacology Read on our Data CenterView on PubMed DOI
  17. Inhibition of c-Jun N-terminal kinase and nuclear factor κ B pathways mediates fisetin-exerted anti-inflammatory activity in lipopolysaccharide-treated RAW264.7 cells Kim SC, Kang SH, Jeong SJ, Kim SH, Ko HS, Kim SH (2012) . Immunopharmacology and Immunotoxicology Read on our Data CenterView on PubMed DOI
  18. Fisetin Promotes Hair Growth by Augmenting TERT Expression Chisato Kubo, Mizuki Ogawa, Norihisa Uehara, Yoshinori Katakura (2020) . Frontiers in Cell and Developmental Biology Read on our Data CenterView on PubMed View on PMC DOI
  19. New Perspectives for Fisetin Grynkiewicz G, Demchuk OM (2019) . Frontiers in Chemistry Read on our Data CenterView on PubMed View on PMC DOI
  20. Intermittent Supplementation With Fisetin Improves Physical Function and Decreases Cellular Senescence in Skeletal Muscle With Aging: A Comparison to Genetic Clearance of Senescent Cells and Synthetic Senolytic Approaches Kevin O. Murray, Sophia A. Mahoney, Katelyn R. Ludwig, Jill H. Miyamoto-Ditmon, Nicholas S. VanDongen, Nirad Banskota, Allison B. Herman, Douglas R. Seals, Robert T. Mankowski, Matthew J. Rossman, Zachary S. Clayton (2025) . Aging Cell Read on our Data CenterView on PubMed View on PMC DOI

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First published 2 Sep 2026 · Last verified 2 Sep 2026