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Characterization and Pharmacokinetic Assessment of a New Berberine Formulation with Enhanced Absorption In Vitro and in Human Volunteers
Pharmaceutics
2023
15(11):2567
Bibliography
- PubMed
- PMID 38004546
- PubMed Central
- PMC10675484
- Trial registry
- View on ClinicalTrials.gov Registered trial — results not yet published in a peer-reviewed journal.
- Funding
- Reported funding sources: Factors Group of Nutritional Companies. Grant and funder-role details are in the publication.
- Competing interests
- Disclosures include Factors Group ownership, consultancy, ISURA employment and formulation-related patent interests.
Study snapshot
| Design | Human formulation pharmacokinetic pilot with in-vitro characterization |
|---|---|
| Model | Human participants; see population |
| Sample | 10 healthy volunteers |
| Intervention | Berberine LipoMicel versus standard berberine; separate laboratory assays |
| Duration | Acute 24-hour pharmacokinetic assessment |
| Endpoints | Plasma exposure and pharmacokinetics; Drug interaction measurements; Short-term tolerability |
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