Tier 2 — strong
Emulsification by vitamin E TPGS or Quillaja extract enhanced absorption of berberine without affecting its metabolism in humans
Food & function
2022
13(23):12135-12143
Bibliography
- PubMed
- PMID 36321951
- Funding
- Indexed support: Florida High Tech Corridor Council. See the publication for grant details.
- Competing interests
- A complete competing-interest declaration was not available in the accessible source; no absence of conflicts is inferred.
Study snapshot
| Design | Randomized crossover formulation pharmacokinetic study |
|---|---|
| Model | Human participants; see population |
| Sample | 12 healthy adults |
| Intervention | Berberine 800 mg as powder or emulsified with vitamin E TPGS or Quillaja extract |
| Duration | Acute 12-hour sampling |
| Endpoints | Plasma exposure and pharmacokinetics; Drug interaction measurements; Short-term tolerability |
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