Tier 3 — preclinical
Displacement of bilirubin from albumin by berberine
Biology of the neonate
1993
63(4):201-208
Bibliography
- PubMed
- PMID 8513024
- Funding
- Funding was not established from the accessible source; this is not a declaration of no funding.
- Competing interests
- A complete competing-interest declaration was not available in the accessible source; no absence of conflicts is inferred.
Study snapshot
| Design | Animal and/or cellular experimental study |
|---|---|
| Model | In-vitro bilirubin-protein binding and adult rats |
| Sample | Bilirubin-binding assays and adult rat groups |
| Intervention | Berberine in vitro and intraperitoneally at 10 or 20 mg/kg/day in rats |
| Duration | 7-day rat exposure |
| Endpoints | Bilirubin-protein binding; Unbound and total bilirubin in rats |
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