Tier 2 — strong
Preventive Effect of Berberine on Postoperative Atrial Fibrillation
Circulation. Arrhythmia and electrophysiology
2022
15(10):e011160
Bibliography
- PubMed
- PMID 36178742
- Funding
- Funding was not established from the accessible source; this is not a declaration of no funding.
- Competing interests
- A complete competing-interest declaration was not available in the accessible source; no absence of conflicts is inferred.
Study snapshot
| Design | Double-blind placebo-controlled randomized CABG trial |
|---|---|
| Model | Human participants; see population |
| Sample | 200 coronary bypass patients; 100 per arm |
| Intervention | Perioperative oral berberine versus placebo |
| Duration | Primary postoperative assessment at 7 days |
| Endpoints | Postoperative atrial fibrillation at 7 days; AF burden and amiodarone use; Inflammatory markers and perioperative outcomes |
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