Short term betaine therapy fails to lower elevated fasting total plasma homocysteine concentrations in hemodialysis patients maintained on chronic folic acid supplementation

A G Bostom, D Shemin, M R Nadeau, V Shih, S P Stabler, R H Allen, J Selhub
Atherosclerosis 1995 113(1):129-132

Bibliography

PubMed
PMID 7755649
DOI
10.1016/0021-9150(94)05466-v
Funding
Funding was not specified in the indexed record or accessible funding metadata.
Competing interests
A competing-interest declaration was not available in the indexed record or accessible disclosure metadata.

Study snapshot

DesignIndexed letter or commentary; abstract unavailable
ModelHuman participants
SampleNot available in the indexed record
InterventionFormulation and dose require the original full report
DurationNot available in the indexed record
EndpointsHistorical or clinical context

What the study showed, in plain terms

Published in 1995, this source examined homocysteine, methylation and vascular function. It is retained for source traceability. Abstract unavailable in PubMed and no accessible full report was verified for this summary. The paper title is not treated as sufficient evidence of efficacy, dose, safety or causality.

The indexed record verifies the publication and citation, but supplies no abstract. A quantitative effect or complete treatment result is not established from this record alone.

Abstract unavailable in PubMed and no accessible full report was verified for this summary. The paper title is not treated as sufficient evidence of efficacy, dose, safety or causality.

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Continue with TMG and Homocysteine: How Much Can Betaine Lower It?

Key findings

  • The indexed record verifies the publication and citation, but supplies no abstract.
  • A quantitative effect or complete treatment result is not established from this record alone.
  • The recorded outcome domains were Historical or clinical context.

What this study can and cannot tell us

  • Abstract unavailable in PubMed and no accessible full report was verified for this summary. The paper title is not treated as sufficient evidence of efficacy, dose, safety or causality.
  • Source basis: Bibliographic data only; no abstract available. Missing method details, funding information or participant denominators are not inferred.

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Damoon Ashtary-Larky et al. · Critical reviews in food science and nutrition · 2022
Tier 2
Effect of homocysteine-lowering nutrients on blood lipids: results from four randomised, placebo-controlled studies in healthy humans
Margreet R Olthof et al. · PLoS medicine · 2005
Tier 2
Betaine supplementation lowers plasma homocysteine in healthy men and women
Gery R Steenge et al. · The Journal of nutrition · 2003
Tier 2
Low dose betaine supplementation leads to immediate and long term lowering of plasma homocysteine in healthy men and women
Margreet R Olthof et al. · The Journal of nutrition · 2003

Editorial review

Reviewed by the Biohack Blueprint research team

Last verified

Dr. Khaled Mahmoud, MBBChCritical Care Medicine, Longevity Science & Editorial Direction Dr. Amr Yasser, PhDCardiometabolic, Musculoskeletal, Gut & Bioavailability Dr. Abdulla Mostafa, PhDCellular Senescence, Neurological, Mitochondrial & Brain-Ageing Biology