Tier 2 — strong

Effect of quercetin supplementation on repeated-sprint performance, xanthine oxidase activity, and inflammation

Elizabeth L Abbey, Janet Walberg Rankin
International journal of sport nutrition and exercise metabolism 2011 21(2):91

Bibliography

PubMed
PMID 21558570
DOI
10.1123/ijsnem.21.2.91
Funding
Funding was not specified in the indexed record or the disclosure metadata available for this entry.
Competing interests
A competing-interest declaration was not available in the indexed record or the disclosure metadata used for this entry.

Study snapshot

DesignPlacebo-controlled crossover repeated-sprint study
ModelHuman intervention research
Sample15 recreationally active young men
InterventionQuercetin-3-glucoside 500 mg twice daily or matched sports drink
Duration1 week per treatment
EndpointsInflammatory measures; Exercise performance or recovery

What the study showed, in plain terms

Published in 2011, this source examined exercise and recovery. Design: Placebo-controlled crossover repeated-sprint study. Sample/model: 15 recreationally active young men. The exposure or intervention was Quercetin-3-glucoside 500 mg twice daily or matched sports drink. Follow-up or treatment period: 1 week per treatment.

Sprint performance and inflammatory or xanthine-oxidase responses did not improve; one fatigue-decrement measure was worse with quercetin.

Small short study of a glucoside formulation. A negative fatigue measure is not sufficient to infer broad harm, but the results do not support a performance benefit.

Continue with Quercetin Data Center

For topic-level interpretation, read Quercetin for Exercise: Performance, Recovery and Muscle. This is a related guide; the citation panel separately identifies articles that directly cite this paper.

Key findings

  • Sprint performance and inflammatory or xanthine-oxidase responses did not improve; one fatigue-decrement measure was worse with quercetin.
  • The recorded outcome domains were Inflammatory measures; Exercise performance or recovery.
  • The result applies to the tested exposure: Quercetin-3-glucoside 500 mg twice daily or matched sports drink; 1 week per treatment.

What this study can and cannot tell us

  • Small short study of a glucoside formulation. A negative fatigue measure is not sufficient to infer broad harm, but the results do not support a performance benefit.
  • An individual controlled trial must be interpreted alongside its comparator, sample size, endpoint selection and independent replication. It does not validate a different commercial formulation or a general longevity claim.
  • Source basis: Source check: PubMed abstract and indexed metadata; full methods were not independently confirmed for this entry. Missing method details, funding information or participant denominators are not inferred.

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Editorial review

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Dr. Khaled Mahmoud, MBBChCritical Care Medicine, Longevity Science & Editorial Direction Dr. Amr Yasser, PhDCardiometabolic, Musculoskeletal, Gut & Bioavailability Dr. Abdulla Mostafa, PhDCellular Senescence, Neurological, Mitochondrial & Brain-Ageing Biology