Tier 1 — highest

Quercetin supplementation promotes recovery after exercise-induced muscle damage: a systematic review and meta-analysis of randomized controlled trials

Daniel Rojano-Ortega, José Peña-Amaro, Antonio J Berral-Aguilar, Francisco J Berral-de la Rosa
Biology of sport 2023 40(3):813-825

Bibliography

PubMed
PMID 37398956
PubMed Central
PMC10286622
DOI
10.5114/biolsport.2023.121320
Funding
Funding was not specified in the indexed record or the disclosure metadata available for this entry.
Competing interests
Reported disclosure: The authors declare no conflict of interest.

Study snapshot

DesignSystematic review and meta-analysis of randomized exercise trials
ModelHuman evidence synthesis
Sample13 studies; 249 participants
InterventionMostly quercetin 1,000 mg/day
DurationSearches through May 31, 2022
EndpointsInflammatory measures; Oxidative-stress measures; Exercise performance or recovery

What the study showed, in plain terms

Published in 2023, this source examined exercise and recovery. Its evidence base was 13 studies; 249 participants. It evaluated Mostly quercetin 1,000 mg/day across Searches through May 31, 2022.

Selected muscle-function, soreness, creatine-kinase, and oxidative-stress outcomes favored supplementation; IL-6 did not improve.

Every included study had some risk-of-bias concerns. Small studies, varied timing, and mostly young male samples limit certainty and generalization.

Continue with Quercetin Data Center

For topic-level interpretation, read Quercetin for Exercise: Performance, Recovery and Muscle. This is a related guide; the citation panel separately identifies articles that directly cite this paper.

Key findings

  • Selected muscle-function, soreness, creatine-kinase, and oxidative-stress outcomes favored supplementation; IL-6 did not improve.
  • The recorded outcome domains were Inflammatory measures; Oxidative-stress measures; Exercise performance or recovery.
  • This synthesis reuses the included study populations; it is not an additional randomized participant cohort.

What this study can and cannot tell us

  • Every included study had some risk-of-bias concerns. Small studies, varied timing, and mostly young male samples limit certainty and generalization.
  • Pooled estimates depend on the included trials and may share participants with companion publications or other reviews. A statistically significant surrogate outcome does not establish disease prevention.
  • Source basis: Source check: PubMed abstract and indexed metadata; full methods were not independently confirmed for this entry. Missing method details, funding information or participant denominators are not inferred.

Related papers in the corpus

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Effects of quercetin supplementation on endurance performance and maximal oxygen consumption: a meta-analysis
Denis M Pelletier et al. · International journal of sport nutrition and exercise metabolism · 2013
Tier 2
Quercetin and endurance exercise capacity: a systematic review and meta-analysis
Jochen Kressler et al. · Medicine and science in sports and exercise · 2011

Citation network

Articles citing this research paper

3 articles

Biohack Blueprint analyses that reference this study in their evidence base.

Editorial review

Reviewed by the Biohack Blueprint research team

Last verified

Dr. Khaled Mahmoud, MBBChCritical Care Medicine, Longevity Science & Editorial Direction Dr. Amr Yasser, PhDCardiometabolic, Musculoskeletal, Gut & Bioavailability Dr. Abdulla Mostafa, PhDCellular Senescence, Neurological, Mitochondrial & Brain-Ageing Biology