Tier 2 — strong

Quercetin's effect on cycling efficiency and substrate utilization

Charles L Dumke, David C Nieman, Alan C Utter, Michael D Rigby, John C Quindry, N Travis Triplett, Steven R McAnulty, Lisa S McAnulty
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2009 34(6):993

Bibliography

PubMed
PMID 20029506
DOI
10.1139/H09-099
Funding
Funding was not specified in the indexed record or the disclosure metadata available for this entry.
Competing interests
A competing-interest declaration was not available in the indexed record or the disclosure metadata used for this entry.

Study snapshot

DesignRandomized placebo-controlled exercise trial
ModelHuman intervention research
Sample40 trained cyclists
InterventionQuercetin 1,000 mg/day or placebo
Duration3 weeks before three consecutive 3-hour cycling days
EndpointsExercise performance or recovery

What the study showed, in plain terms

Published in 2009, this source examined exercise and recovery. Design: Randomized placebo-controlled exercise trial. Sample/model: 40 trained cyclists. The exposure or intervention was Quercetin 1,000 mg/day or placebo. Follow-up or treatment period: 3 weeks before three consecutive 3-hour cycling days.

Quercetin did not improve cycling efficiency, substrate use, perceived effort, or measured metabolic responses.

Short trial in trained cyclists; results may share a research program with related exercise reports and should not be treated as proof of benefit in other populations.

Continue with Quercetin Data Center

For topic-level interpretation, read Quercetin for Exercise: Performance, Recovery and Muscle. This is a related guide; the citation panel separately identifies articles that directly cite this paper.

Key findings

  • Quercetin did not improve cycling efficiency, substrate use, perceived effort, or measured metabolic responses.
  • The recorded outcome domains were Exercise performance or recovery.
  • The result applies to the tested exposure: Quercetin 1,000 mg/day or placebo; 3 weeks before three consecutive 3-hour cycling days.

What this study can and cannot tell us

  • Short trial in trained cyclists; results may share a research program with related exercise reports and should not be treated as proof of benefit in other populations.
  • An individual controlled trial must be interpreted alongside its comparator, sample size, endpoint selection and independent replication. It does not validate a different commercial formulation or a general longevity claim.
  • Source basis: Source check: PubMed abstract and indexed metadata; full methods were not independently confirmed for this entry. Missing method details, funding information or participant denominators are not inferred.

Related papers in the corpus

Tier 1
Quercetin supplementation promotes recovery after exercise-induced muscle damage: a systematic review and meta-analysis of randomized controlled trials
Daniel Rojano-Ortega et al. · Biology of sport · 2023
Tier 2
Effects of quercetin supplementation on endurance performance and maximal oxygen consumption: a meta-analysis
Denis M Pelletier et al. · International journal of sport nutrition and exercise metabolism · 2013
Tier 2
Short-Term Oral Quercetin Supplementation Improves Post-exercise Insulin Sensitivity, Antioxidant Capacity and Enhances Subsequent Cycling Time to Exhaustion in Healthy Adults: A Pilot Study
Jung-Piao Tsao et al. · Frontiers in nutrition · 2022
Tier 2
Effects of vitamin D and quercetin, alone and in combination, on cardiorespiratory fitness and muscle function in physically active male adults
Shane D Scholten et al. · Open access journal of sports medicine · 2015
Tier 2
The effects of quercetin supplementation on body composition, exercise performance and muscle damage indices in athletes
Gholamreza Askari et al. · International journal of preventive medicine · 2013

Editorial review

Reviewed by the Biohack Blueprint research team

Last verified

Dr. Khaled Mahmoud, MBBChCritical Care Medicine, Longevity Science & Editorial Direction Dr. Amr Yasser, PhDCardiometabolic, Musculoskeletal, Gut & Bioavailability Dr. Abdulla Mostafa, PhDCellular Senescence, Neurological, Mitochondrial & Brain-Ageing Biology