Tier 2 — strong

Magnesium bioavailability from magnesium citrate and magnesium oxide

J S Lindberg, M M Zobitz, J R Poindexter, C Y Pak
Journal of the American College of Nutrition 1990 9(1):48-55

Bibliography

PubMed
PMID 2407766
DOI
10.1080/07315724.1990.10720349
Funding
Support is recorded from NCRR NIH HHS, NIDDK NIH HHS, NIAMS NIH HHS. See the original publication for grant and material-support details.
Competing interests
A competing-interest declaration is not available in the indexed abstract or accessible disclosure metadata.

Study snapshot

DesignComparative absorption study with laboratory solubility testing
ModelHuman participants
SampleHealthy volunteers; no sample total in the indexed abstract
InterventionSingle 25 mmol magnesium loads as citrate or oxide
DurationAcute post-dose monitoring
EndpointsMagnesium solubility; Urinary magnesium excretion

What the study showed, in plain terms

This publication examines magnesium solubility, urinary magnesium excretion. Study population or evidence base: Healthy volunteers; no sample total in the indexed abstract. Intervention or exposure: Single 25 mmol magnesium loads as citrate or oxide.

Key findings

Magnesium citrate was more soluble and produced greater post-dose urinary magnesium excretion than oxide in the tested conditions.

What this study can and cannot tell us

An acute absorption comparison does not establish long-term clinical superiority or compare either salt directly with magnesium L-threonate.

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