Tier 2 — strong

Effects of berberine and barberry on anthropometric measures: A systematic review and meta-analysis of randomized controlled trials

Amini MR, Sheikhhossein F, Naghshi S, Djafari F, Askari M, Shahinfar H, Safabakhsh M, Jafari A, Shab-Bidar S
Complementary therapies in medicine 2020 49:102337

Bibliography

PubMed
PMID 32147051
DOI
10.1016/j.ctim.2020.102337
Funding
Funding was not established from the accessible source; this is not a declaration of no funding.
Competing interests
A complete competing-interest declaration was not available in the accessible source; no absence of conflicts is inferred.

Study snapshot

DesignSystematic review and meta-analysis
ModelPublished human studies
Sample12 trials; 849 participants
InterventionEvidence synthesis; interventions and comparators vary across included studies
DurationNo new treatment; included-study durations vary
EndpointsPooled clinical or metabolic outcomes; Risk of bias and heterogeneity; Adverse-event reporting

What the study showed, in plain terms

The review found no significant BMI or weight effect, while waist-to-hip ratio improved in berberine comparisons.

Key findings

  • The review found no significant BMI or weight effect, while waist-to-hip ratio improved in berberine comparisons.

What this study can and cannot tell us

Combines berberine and barberry preparations; retain null outcomes and formulation differences.

Source detail: indexed abstract and bibliographic record; unavailable methods or disclosures are identified rather than assumed.

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Dr. Khaled Mahmoud, MBBChCritical Care Medicine, Longevity Science & Editorial Direction Dr. Amr Yasser, PhDCardiometabolic, Musculoskeletal, Gut & Bioavailability Dr. Abdulla Mostafa, PhDCellular Senescence, Neurological, Mitochondrial & Brain-Ageing Biology