Tier 3 — preclinical

Berberine: Botanical Occurrence, Traditional Uses, Extraction Methods, and Relevance in Cardiovascular, Metabolic, Hepatic, and Renal Disorders

Neag MA, Mocan A, Echeverría J, Pop RM, Bocsan CI, Crişan G, Buzoianu AD
Frontiers in pharmacology 2018 9:557

Bibliography

PubMed
PMID 30186157
PubMed Central
PMC6111450
Funding
Not stated as a separate funding declaration in the accessible full text.
Competing interests
Authors declare no commercial or financial relationships that could be construed as a potential conflict of interest.

Study snapshot

DesignNarrative botanical and pharmacology review
ModelPublished literature
SampleNo new human trial; literature review
InterventionBerberine-containing plants, extraction methods and experimental pharmacology
DurationNot applicable
EndpointsBotanical occurrence and plant tissues; Extraction and quantification methods; Experimental pharmacology and clinical translation

What the study showed, in plain terms

Berberine occurrence depends on species and plant tissue; the paper reviews botanical sources and extraction rather than a standardized dietary food-content database.

Key findings

Berberine occurrence depends on species and plant tissue; the paper reviews botanical sources and extraction rather than a standardized dietary food-content database.

What this study can and cannot tell us

Narrative review mixes traditional use, laboratory findings and clinical studies. It cannot establish a clinical dose from culinary fruit, tea or an unspecified plant extract.

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