Tier 2 — strong

[Therapeutic Effects of Berberine Capsule on Patients with Mild Hyperlipidemia]

Wang L, Peng LY, Wei GH, Ge H

Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 2016 36(6):681-684

Bibliography

PubMed: PMID 27491226
Funding: Funding was not established from the accessible source; this is not a declaration of no funding.
Competing interests: A complete competing-interest declaration was not available in the accessible source; no absence of conflicts is inferred.

Design	Randomized controlled human trial
Model	Human participants; see population
Sample	102 recruited; 97 randomized after run-in
Intervention	Berberine capsules 300 mg three times/day versus placebo
Duration	Two 3-month periods with a 2-month washout
Endpoints	Total and LDL cholesterol; Triglycerides and apolipoproteins; Metabolic and vascular biomarkers

This controlled trial reported lipid-profile improvement during berberine treatment in mild hyperlipidemia.

This controlled trial reported lipid-profile improvement during berberine treatment in mild hyperlipidemia.

A single population and lipid endpoints limit outcome inference. The English indexed abstract has incomplete numerical results.

Source detail: indexed abstract and bibliographic record; unavailable methods or disclosures are identified rather than assumed.

Editorial review

Last verified 22 October 2026