Tier 2 — strong
Effects of berberine on lipid profile in subjects with low cardiovascular risk
Expert opinion on biological therapy
2013
13(4):475-482
Bibliography
- PubMed
- PMID 23441841
- Funding
- Funding was not established from the accessible source; this is not a declaration of no funding.
- Competing interests
- A complete competing-interest declaration was not available in the accessible source; no absence of conflicts is inferred.
Study snapshot
| Design | Double-blind placebo-controlled withdrawal and reintroduction trial |
|---|---|
| Model | Human participants; see population |
| Sample | 144 adults at low cardiovascular risk |
| Intervention | Berberine 500 mg twice/day versus placebo, with diet/activity |
| Duration | Two 3-month treatment periods separated by 2-month washout |
| Endpoints | Total and LDL cholesterol; Triglycerides and apolipoproteins; Metabolic and vascular biomarkers |
What the study showed, in plain terms
Key findings
What this study can and cannot tell us
Editorial review
Reviewed by the Biohack Blueprint research team
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