Tier 2 — strong

Efficacy of quercetin and the role of endothelial protection in the treatment of patients with arterial hypertension

Valentyna Volodymyrivna Chopyak, Igor Grygorovich Hayduchok, Yuriy Volodymyrovych Fedorov, Alona Vasylivna Kovpak, Bogdana Fedorivna Baida, Oksana Volodymyrivna Levytska, Volodymyr Antonovych Doroshko
Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 2025 74(4):2-7

Bibliography

PubMed
PMID 41412805
DOI
10.36290/csf.2025.036
Funding
Funding was not specified in the indexed record or the disclosure metadata available for this entry.
Competing interests
A competing-interest declaration was not available in the indexed record or the disclosure metadata used for this entry.

Study snapshot

DesignComparative adjunct-treatment clinical study
ModelHuman intervention research
Sample120 patients with stage 2 hypertension
InterventionCorvitin quercetin plus ramipril/amlodipine versus standard therapy alone
DurationDose, route, and duration not stated in the indexed abstract
EndpointsBlood pressure; Inflammatory measures

What the study showed, in plain terms

Published in 2025, this source examined cardiovascular and metabolic health. Design: Comparative adjunct-treatment clinical study. Sample/model: 120 patients with stage 2 hypertension. The exposure or intervention was Corvitin quercetin plus ramipril/amlodipine versus standard therapy alone. Follow-up or treatment period: Dose, route, and duration not stated in the indexed abstract.

The report describes improved ambulatory pressure profiles and selected endothelial or inflammatory markers with adjunct treatment.

Randomization and masking are not established in the abstract. Findings for a medicinal quercetin formulation cannot be assumed to apply to consumer capsules or clinical event prevention.

Continue with Quercetin Data Center

For topic-level interpretation, read Quercetin and Blood Pressure: How Large Is the Effect?. This is a related guide; the citation panel separately identifies articles that directly cite this paper.

Key findings

  • The report describes improved ambulatory pressure profiles and selected endothelial or inflammatory markers with adjunct treatment.
  • The recorded outcome domains were Blood pressure; Inflammatory measures.
  • The result applies to the tested exposure: Corvitin quercetin plus ramipril/amlodipine versus standard therapy alone; Dose, route, and duration not stated in the indexed abstract.

What this study can and cannot tell us

  • Randomization and masking are not established in the abstract. Findings for a medicinal quercetin formulation cannot be assumed to apply to consumer capsules or clinical event prevention.
  • An individual controlled trial must be interpreted alongside its comparator, sample size, endpoint selection and independent replication. It does not validate a different commercial formulation or a general longevity claim.
  • Source basis: Source check: PubMed abstract and indexed metadata; full methods were not independently confirmed for this entry. Missing method details, funding information or participant denominators are not inferred.

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INDICATORS OF ENDOTHELIAL DYSFUNCTION, MARKERS OF INFLAMMATION AND LIPID METABOLISM IN PATIENTS WITH HYPERTENSION WITH THE ADMINISTRATION OF QUERCETIN
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Supplementation of the Pure Flavonoids Epicatechin and Quercetin Affects Some Biomarkers of Endothelial Dysfunction and Inflammation in (Pre)Hypertensive Adults: A Randomized Double-Blind, Placebo-Controlled, Crossover Trial
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Editorial review

Reviewed by the Biohack Blueprint research team

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Dr. Khaled Mahmoud, MBBChCritical Care Medicine, Longevity Science & Editorial Direction Dr. Amr Yasser, PhDCardiometabolic, Musculoskeletal, Gut & Bioavailability Dr. Abdulla Mostafa, PhDCellular Senescence, Neurological, Mitochondrial & Brain-Ageing Biology