Tier 2 — strong

Hypocholesterolemic Efficacy of Quercetin Rich Onion Juice in Healthy Mild Hypercholesterolemic Adults: A Pilot Study

Tsong-Ming Lu, Hui-Fang Chiu, You-Cheng Shen, Chia-Chun Chung, Kamesh Venkatakrishnan, Chin-Kun Wang
Plant foods for human nutrition (Dordrecht, Netherlands) 2015 70(4):395-400

Bibliography

PubMed
PMID 26385226
DOI
10.1007/s11130-015-0507-4
Funding
Funding was not specified in the indexed record or the disclosure metadata available for this entry.
Competing interests
A competing-interest declaration was not available in the indexed record or the disclosure metadata used for this entry.

Study snapshot

DesignPlacebo-comparator dietary pilot
ModelHuman intervention research
Sample24 adults with mildly elevated cholesterol
InterventionOnion juice 100 mL/day or placebo
Duration8 weeks
EndpointsLipid measurements; Oxidative-stress measures

What the study showed, in plain terms

Published in 2015, this source examined cardiovascular and metabolic health. Design: Placebo-comparator dietary pilot. Sample/model: 24 adults with mildly elevated cholesterol. The exposure or intervention was Onion juice 100 mL/day or placebo. Follow-up or treatment period: 8 weeks.

Selected cholesterol, waist, and antioxidant measures improved in the onion-juice group.

Small whole-food study with incompletely described allocation. Effects cannot be isolated to quercetin or treated as evidence that capsules prevent cardiovascular disease.

Continue with Quercetin Data Center

For topic-level interpretation, read Quercetin for Weight Loss, Blood Sugar and Fatty Liver: Human Evidence. This is a related guide; the citation panel separately identifies articles that directly cite this paper.

Key findings

  • Selected cholesterol, waist, and antioxidant measures improved in the onion-juice group.
  • The recorded outcome domains were Lipid measurements; Oxidative-stress measures.
  • The result applies to the tested exposure: Onion juice 100 mL/day or placebo; 8 weeks.

What this study can and cannot tell us

  • Small whole-food study with incompletely described allocation. Effects cannot be isolated to quercetin or treated as evidence that capsules prevent cardiovascular disease.
  • An individual controlled trial must be interpreted alongside its comparator, sample size, endpoint selection and independent replication. It does not validate a different commercial formulation or a general longevity claim.
  • Source basis: Source check: PubMed abstract and indexed metadata; full methods were not independently confirmed for this entry. Missing method details, funding information or participant denominators are not inferred.

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Editorial review

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Dr. Khaled Mahmoud, MBBChCritical Care Medicine, Longevity Science & Editorial Direction Dr. Amr Yasser, PhDCardiometabolic, Musculoskeletal, Gut & Bioavailability Dr. Abdulla Mostafa, PhDCellular Senescence, Neurological, Mitochondrial & Brain-Ageing Biology