Tier 2 — strong

Quercetin loaded cosm-nutraceutical electrospun composite nanofibers for acne alleviation: Preparation, characterization and experimental clinical appraisal

Sandra Sherif Amer, Wael Mamdouh, Maha Nasr, Amr ElShaer, Elena Polycarpou, Rasha T A Abdel-Aziz, Omaima A Sammour
International journal of pharmaceutics 2022 612:121309

Bibliography

PubMed
PMID 34801653
DOI
10.1016/j.ijpharm.2021.121309
Funding
Funding was not specified in the indexed record or the disclosure metadata available for this entry.
Competing interests
A competing-interest declaration was not available in the indexed record or the disclosure metadata used for this entry.

Study snapshot

DesignLaboratory formulation research with exploratory clinical evaluation
ModelHuman intervention research
SampleAcne-patient cohort; size not stated in abstract
InterventionTopical quercetin/essential-oil nanofiber formulation
DurationClinical exposure duration not stated in abstract
EndpointsSource-specific outcomes described in the key findings

What the study showed, in plain terms

Published in 2022, this source examined skin and topical formulations. Design: Laboratory formulation research with exploratory clinical evaluation. Sample/model: Acne-patient cohort; size not stated in abstract. The exposure or intervention was Topical quercetin/essential-oil nanofiber formulation. Follow-up or treatment period: Clinical exposure duration not stated in abstract.

The nanofiber system showed antibacterial activity and reductions in acne lesions in the exploratory patient assessment.

Unclear clinical allocation details in the abstract and multiple topical ingredients. No oral-supplement benefit was tested.

Continue with Quercetin Data Center

For topic-level interpretation, read Quercetin for Skin and Hair: Oral vs Topical Evidence. This is a related guide; the citation panel separately identifies articles that directly cite this paper.

Key findings

  • The nanofiber system showed antibacterial activity and reductions in acne lesions in the exploratory patient assessment.
  • The recorded outcome domains were Source-specific outcomes described in the key findings.
  • The result applies to the tested exposure: Topical quercetin/essential-oil nanofiber formulation; Clinical exposure duration not stated in abstract.

What this study can and cannot tell us

  • Unclear clinical allocation details in the abstract and multiple topical ingredients. No oral-supplement benefit was tested.
  • An individual controlled trial must be interpreted alongside its comparator, sample size, endpoint selection and independent replication. It does not validate a different commercial formulation or a general longevity claim.
  • Source basis: Source check: PubMed abstract and indexed metadata; full methods were not independently confirmed for this entry. Missing method details, funding information or participant denominators are not inferred.

Related papers in the corpus

Tier 2
Quercetin as a Natural Adjunct in Managing Plaque and Gingivitis in Adults: A Randomized Controlled Trial
Ankita Rawal et al. · Cureus · 2026
Tier 2
Efficacy and Safety of Topical Compound Heparin Sodium Allantoin Gel (Main Components: Onion Extract Quercetin) for the Treatment of Rosacea
Zining Xu et al. · Journal of cosmetic dermatology · 2025
Tier 2
Nano-hydrogel embedded with quercetin and oleic acid as a new formulation in the treatment of diabetic foot ulcer: A pilot study
Giuseppe Gallelli et al. · International wound journal · 2020

Citation network

Articles citing this research paper

1 article

Biohack Blueprint analyses that reference this study in their evidence base.

Editorial review

Reviewed by the Biohack Blueprint research team

Last verified

Dr. Khaled Mahmoud, MBBChCritical Care Medicine, Longevity Science & Editorial Direction Dr. Amr Yasser, PhDCardiometabolic, Musculoskeletal, Gut & Bioavailability Dr. Abdulla Mostafa, PhDCellular Senescence, Neurological, Mitochondrial & Brain-Ageing Biology