Tier 1 — highest

Effect of quercetin supplementation on plasma lipid profiles, blood pressure, and glucose levels: a systematic review and meta-analysis

Haohai Huang, Dan Liao, Yong Dong, Rong Pu
Nutrition reviews 2020 78(8):615-626

Bibliography

PubMed
PMID 31940027
DOI
10.1093/nutrit/nuz071
Funding
Funding was not specified in the indexed record or the disclosure metadata available for this entry.
Competing interests
A competing-interest declaration was not available in the indexed record or the disclosure metadata used for this entry.

Study snapshot

DesignSystematic review and meta-analysis of randomized trials
ModelHuman evidence synthesis
Sample17 trials; 896 participants
InterventionQuercetin or standardized quercetin-enriched extracts
DurationSearches through July 2018
EndpointsBlood pressure; Lipid measurements; Glucose and insulin measures

What the study showed, in plain terms

Published in 2020, this source examined cardiovascular and metabolic health. Its evidence base was 17 trials; 896 participants. It evaluated Quercetin or standardized quercetin-enriched extracts across Searches through July 2018.

Pooled systolic and diastolic pressure decreased; overall lipid and glucose outcomes were not significantly changed.

Heterogeneous short interventions and surrogate measures. Positive subgroup findings do not replace null overall lipid or glucose results.

Continue with Quercetin Data Center

For topic-level interpretation, read Quercetin and Blood Pressure: How Large Is the Effect?. This is a related guide; the citation panel separately identifies articles that directly cite this paper.

Key findings

  • Pooled systolic and diastolic pressure decreased; overall lipid and glucose outcomes were not significantly changed.
  • The recorded outcome domains were Blood pressure; Lipid measurements; Glucose and insulin measures.
  • This synthesis reuses the included study populations; it is not an additional randomized participant cohort.

What this study can and cannot tell us

  • Heterogeneous short interventions and surrogate measures. Positive subgroup findings do not replace null overall lipid or glucose results.
  • Pooled estimates depend on the included trials and may share participants with companion publications or other reviews. A statistically significant surrogate outcome does not establish disease prevention.
  • Source basis: Source check: PubMed abstract and indexed metadata; full methods were not independently confirmed for this entry. Missing method details, funding information or participant denominators are not inferred.

Related papers in the corpus

Tier 1
The effects of Quercetin supplementation on cardiometabolic outcomes: An umbrella review of meta-analyses of randomized controlled trials
Seyyed Mostafa Arabi et al. · Phytotherapy research : PTR · 2023
Tier 1
The Effects of Quercetin Supplementation on Blood Pressure - Meta-Analysis
Joanna Popiolek-Kalisz et al. · Current problems in cardiology · 2022
Tier 1
The effects of quercetin supplementation on lipid profiles and inflammatory markers among patients with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized controlled trials
Reza Tabrizi et al. · Critical reviews in food science and nutrition · 2020

Editorial review

Reviewed by the Biohack Blueprint research team

Last verified

Dr. Khaled Mahmoud, MBBChCritical Care Medicine, Longevity Science & Editorial Direction Dr. Amr Yasser, PhDCardiometabolic, Musculoskeletal, Gut & Bioavailability Dr. Abdulla Mostafa, PhDCellular Senescence, Neurological, Mitochondrial & Brain-Ageing Biology