Tier 1 — highest

Effects of quercetin supplementation on lipid profile: A systematic review and meta-analysis of randomized controlled trials

Amirhossein Sahebkar
Critical reviews in food science and nutrition 2017 57(4):666

Bibliography

PubMed
PMID 25897620
DOI
10.1080/10408398.2014.948609
Funding
Funding was not specified in the indexed record or the disclosure metadata available for this entry.
Competing interests
A competing-interest declaration was not available in the indexed record or the disclosure metadata used for this entry.

Study snapshot

DesignSystematic review and meta-analysis of randomized trials
ModelHuman evidence synthesis
Sample5 trials; 442 participants
InterventionQuercetin across trial-specific regimens
DurationLiterature available at the review cutoff
EndpointsLipid measurements

What the study showed, in plain terms

Published in 2017, this source examined cardiovascular and metabolic health. Its evidence base was 5 trials; 442 participants. It evaluated Quercetin across trial-specific regimens across Literature available at the review cutoff.

Overall LDL, HDL, and triglyceride outcomes were not significantly improved; selected dose-duration subgroups showed triglyceride changes.

The abstract contains inconsistent dose wording in its conclusion; subgroup estimates do not establish a reliable universal threshold or clinically meaningful lipid treatment.

Continue with Quercetin Data Center

For topic-level interpretation, read Quercetin for Weight Loss, Blood Sugar and Fatty Liver: Human Evidence. This is a related guide; the citation panel separately identifies articles that directly cite this paper.

Key findings

  • Overall LDL, HDL, and triglyceride outcomes were not significantly improved; selected dose-duration subgroups showed triglyceride changes.
  • The recorded outcome domains were Lipid measurements.
  • This synthesis reuses the included study populations; it is not an additional randomized participant cohort.

What this study can and cannot tell us

  • The abstract contains inconsistent dose wording in its conclusion; subgroup estimates do not establish a reliable universal threshold or clinically meaningful lipid treatment.
  • Pooled estimates depend on the included trials and may share participants with companion publications or other reviews. A statistically significant surrogate outcome does not establish disease prevention.
  • Source basis: Source check: PubMed abstract and indexed metadata; full methods were not independently confirmed for this entry. Missing method details, funding information or participant denominators are not inferred.

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Editorial review

Reviewed by the Biohack Blueprint research team

Last verified

Dr. Khaled Mahmoud, MBBChCritical Care Medicine, Longevity Science & Editorial Direction Dr. Amr Yasser, PhDCardiometabolic, Musculoskeletal, Gut & Bioavailability Dr. Abdulla Mostafa, PhDCellular Senescence, Neurological, Mitochondrial & Brain-Ageing Biology