Tier 2 — strong

Quercetin and vitamin C supplementation: effects on lipid profile and muscle damage in male athletes

Gholamreza Askari, Maryam Hajishafiee, Reza Ghiasvand, Mitra Hariri, Leila Darvishi, Shekoofeh Ghassemi, Bijan Iraj, Volga Hovsepian
International journal of preventive medicine 2013 4(Suppl 1):S58-62

Bibliography

PubMed
PMID 23717772
PubMed Central
PMC3665028
Funding
Funding was not specified in the indexed record or the disclosure metadata available for this entry.
Competing interests
Reported disclosure: None declared

Study snapshot

DesignRandomized double-blind placebo-controlled four-arm athlete trial
ModelHuman intervention research
Sample60 men
InterventionQuercetin 500 mg/day, vitamin C, their combination, or placebo
Duration8 weeks
EndpointsLipid measurements

What the study showed, in plain terms

Published in 2013, this source examined exercise and recovery. Design: Randomized double-blind placebo-controlled four-arm athlete trial. Sample/model: 60 men. The exposure or intervention was Quercetin 500 mg/day, vitamin C, their combination, or placebo. Follow-up or treatment period: 8 weeks.

The abstract reports a within-group LDL decrease with the combination, without a clear between-group lipid benefit.

Vitamin C dose descriptions vary between arms and related reports. Within-group findings and likely shared athlete cohorts prevent strong isolated-quercetin claims.

Continue with Quercetin Data Center

For topic-level interpretation, read Quercetin for Exercise: Performance, Recovery and Muscle. This is a related guide; the citation panel separately identifies articles that directly cite this paper.

Key findings

  • The abstract reports a within-group LDL decrease with the combination, without a clear between-group lipid benefit.
  • The recorded outcome domains were Lipid measurements.
  • The result applies to the tested exposure: Quercetin 500 mg/day, vitamin C, their combination, or placebo; 8 weeks.

What this study can and cannot tell us

  • Vitamin C dose descriptions vary between arms and related reports. Within-group findings and likely shared athlete cohorts prevent strong isolated-quercetin claims.
  • An individual controlled trial must be interpreted alongside its comparator, sample size, endpoint selection and independent replication. It does not validate a different commercial formulation or a general longevity claim.
  • Companion or correction records are linked below. They should not be counted automatically as independent replications; see the individual source notes for the relationship.
  • Source basis: Source check: PubMed abstract and indexed metadata; full methods were not independently confirmed for this entry. Missing method details, funding information or participant denominators are not inferred.

Related papers in the corpus

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The effects of quercetin supplementation on body composition, exercise performance and muscle damage indices in athletes
Gholamreza Askari et al. · International journal of preventive medicine · 2013
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Does quercetin and vitamin C improve exercise performance, muscle damage, and body composition in male athletes?
Gholamreza Askari et al. · Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2012
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The effect of quercetin supplementation on selected markers of inflammation and oxidative stress
Gholamreza Askari et al. · Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2012
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Quercetin supplementation promotes recovery after exercise-induced muscle damage: a systematic review and meta-analysis of randomized controlled trials
Daniel Rojano-Ortega et al. · Biology of sport · 2023
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Effects of quercetin supplementation on endurance performance and maximal oxygen consumption: a meta-analysis
Denis M Pelletier et al. · International journal of sport nutrition and exercise metabolism · 2013

Editorial review

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Dr. Khaled Mahmoud, MBBChCritical Care Medicine, Longevity Science & Editorial Direction Dr. Amr Yasser, PhDCardiometabolic, Musculoskeletal, Gut & Bioavailability Dr. Abdulla Mostafa, PhDCellular Senescence, Neurological, Mitochondrial & Brain-Ageing Biology