Tier 2 — strong

Quercetin with vitamin C and niacin does not affect body mass or composition

Amy M Knab, R Andrew Shanely, Fuxia Jin, Melanie D Austin, Wei Sha, David C Nieman
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2011 36(3):331

Bibliography

PubMed
PMID 21574787
DOI
10.1139/h11-015
Funding
Funding was not specified in the indexed record or the disclosure metadata available for this entry.
Competing interests
A competing-interest declaration was not available in the indexed record or the disclosure metadata used for this entry.

Study snapshot

DesignRandomized double-blind placebo-controlled body-composition analysis
ModelHuman intervention research
Sample941 adults with body-composition data
InterventionQuercetin 500 or 1,000 mg/day with vitamin C and niacin, or placebo
Duration12 weeks
EndpointsSource-specific outcomes described in the key findings

What the study showed, in plain terms

Published in 2011, this source examined liver and metabolic health. Design: Randomized double-blind placebo-controlled body-composition analysis. Sample/model: 941 adults with body-composition data. The exposure or intervention was Quercetin 500 or 1,000 mg/day with vitamin C and niacin, or placebo. Follow-up or treatment period: 12 weeks.

Body mass and composition did not improve, including among participants with overweight or obesity.

Same wider community research program as other reports; multi-ingredient supplementation and short duration limit broader inference.

Continue with Quercetin Data Center

For topic-level interpretation, read Quercetin for Weight Loss, Blood Sugar and Fatty Liver: Human Evidence. This is a related guide; the citation panel separately identifies articles that directly cite this paper.

Key findings

  • Body mass and composition did not improve, including among participants with overweight or obesity.
  • The recorded outcome domains were Source-specific outcomes described in the key findings.
  • The result applies to the tested exposure: Quercetin 500 or 1,000 mg/day with vitamin C and niacin, or placebo; 12 weeks.

What this study can and cannot tell us

  • Same wider community research program as other reports; multi-ingredient supplementation and short duration limit broader inference.
  • An individual controlled trial must be interpreted alongside its comparator, sample size, endpoint selection and independent replication. It does not validate a different commercial formulation or a general longevity claim.
  • Companion or correction records are linked below. They should not be counted automatically as independent replications; see the individual source notes for the relationship.
  • Source basis: Source check: PubMed abstract and indexed metadata; full methods were not independently confirmed for this entry. Missing method details, funding information or participant denominators are not inferred.

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Citation network

Articles citing this research paper

2 articles

Biohack Blueprint analyses that reference this study in their evidence base.

Editorial review

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Dr. Khaled Mahmoud, MBBChCritical Care Medicine, Longevity Science & Editorial Direction Dr. Amr Yasser, PhDCardiometabolic, Musculoskeletal, Gut & Bioavailability Dr. Abdulla Mostafa, PhDCellular Senescence, Neurological, Mitochondrial & Brain-Ageing Biology