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Berberine as adjuvant therapy for treating reduced fertility potential in women with polycystic ovary syndrome: A meta-analysis of randomized controlled trials

Ha S, Song X

Explore (New York, N.Y.) 2024 20(6):103040

Bibliography

PubMed: PMID 39236662
DOI: 10.1016/j.explore.2024.103040
Funding: Funding was not established from the accessible source; this is not a declaration of no funding.
Competing interests: A complete competing-interest declaration was not available in the accessible source; no absence of conflicts is inferred.

Design	Systematic review and meta-analysis
Model	Published human studies
Sample	10 randomized trials; 713 participants
Intervention	Evidence synthesis; interventions and comparators vary across included studies
Duration	No new treatment; included-study durations vary
Endpoints	Pooled clinical or metabolic outcomes; Risk of bias and heterogeneity; Adverse-event reporting

The add-on synthesis reported higher ovulation and clinical-pregnancy rates alongside selected hormonal changes.

The add-on synthesis reported higher ovulation and clinical-pregnancy rates alongside selected hormonal changes.

Pregnancy rate is not live birth; cointerventions and the later 2026 integrity concerns substantially limit efficacy claims.

Source detail: indexed abstract and bibliographic record; unavailable methods or disclosures are identified rather than assumed.

Editorial review

Last verified 22 October 2026