Tier 4 — mechanistic
Lipid profiling of the therapeutic effects of berberine in patients with nonalcoholic fatty liver disease
Journal of translational medicine
2016
14:266
Bibliography
- PubMed
- PMID 27629750
- PubMed Central
- PMC5024486
- Trial registry
- View on ClinicalTrials.gov Registered trial — results not yet published in a peer-reviewed journal.
- Funding
- Reported funding sources: the National Key Basic Research Program of China; the Shanghai Municipal Health Project grant; the Shanghai Health and Family Planning Commission Foundation; Science and Technology Commission of Shanghai Municipality. Grant and funder-role details are in the publication.
- Competing interests
- The authors declared no competing interests in the publication.
Study snapshot
| Design | Companion lipidomic analysis of a randomized trial |
|---|---|
| Model | Human participants; see population |
| Sample | 41 berberine and 39 lifestyle participants from NCT00633282 |
| Intervention | Serum lipidomics from the earlier NAFLD randomized trial |
| Duration | 16 weeks |
| Endpoints | Liver fat and liver enzymes; Body composition and weight; Metabolic biomarkers |
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