Tier 2 — strong

The Therapeutic Effect of Berberine in the Treatment of Nonalcoholic Fatty Liver Disease: A Meta-Analysis

Wei X, Wang C, Hao S, Song H, Yang L
Evidence-based complementary and alternative medicine : eCAM 2016 2016:3593951

Bibliography

PubMed
PMID 27446224
PubMed Central
PMC4947506
Funding
Indexed support: Leading Academic Discipline Project; Shanghai Municipal Commission of Health and Family Planning; Natural Science Foundation of Shanghai. See the publication for grant details.
Competing interests
The authors declared no competing interests in the publication.

Study snapshot

DesignSystematic review and meta-analysis
ModelPublished human studies
Sample6 randomized trials; 501 participants
InterventionEvidence synthesis; interventions and comparators vary across included studies
DurationNo new treatment; included-study durations vary
EndpointsPooled clinical or metabolic outcomes; Risk of bias and heterogeneity; Adverse-event reporting

What the study showed, in plain terms

The historical synthesis reported selected lipid, glucose and liver-enzyme changes in NAFLD.

Key findings

  • The historical synthesis reported selected lipid, glucose and liver-enzyme changes in NAFLD.

What this study can and cannot tell us

Small and variable-quality studies; newer evidence, including null results, is needed for current interpretation.

Editorial review

Reviewed by the Biohack Blueprint research team

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