Tier 2 — strong

The effects of berberine on blood lipids: a systemic review and meta-analysis of randomized controlled trials

Dong H, Zhao Y, Zhao L, Lu F

Planta medica 2013 79(6):437-446

Bibliography

PubMed: PMID 23512497
DOI: 10.1055/s-0032-1328321
Funding: Funding was not established from the accessible source; this is not a declaration of no funding.
Competing interests: A complete competing-interest declaration was not available in the accessible source; no absence of conflicts is inferred.

Design	Systematic review and meta-analysis
Model	Published human studies
Sample	11 randomized trials; 874 participants
Intervention	Evidence synthesis; interventions and comparators vary across included studies
Duration	No new treatment; included-study durations vary
Endpoints	Pooled clinical or metabolic outcomes; Risk of bias and heterogeneity; Adverse-event reporting

The early synthesis reported lower cholesterol and triglycerides, with a small HDL change.

The early synthesis reported lower cholesterol and triglycerides, with a small HDL change.

The authors judged methodological quality generally low; retained for the historical development of the evidence.

Source detail: indexed abstract and bibliographic record; unavailable methods or disclosures are identified rather than assumed.

Editorial review

Last verified 22 October 2026