Tier 3 — preclinical
Absorption of bioactive peptides following collagen hydrolysate intake: a randomized, double-blind crossover study in healthy individuals
Frontiers in Nutrition
2024
11:1416643
Bibliography
- PubMed
- PMID 39149544
- PubMed Central
- PMC11325589
- Funding
- Funded by Rousselot BV.
- Competing interests
- Five authors employed by Rousselot BV; remaining investigators employed by contracted BioTeSys and Triskelion.
Study snapshot
| Design | Randomized double-blind four-treatment crossover pharmacokinetic pilot |
|---|---|
| Model | Healthy young nonsmokers; mean age 25.2 years |
| Sample | 6 healthy volunteers (3 women, 3 men) |
| Intervention | 10 g single doses of fish, porcine and bovine collagen hydrolysates (bovine ~2,000 Da and ~5,000 Da) |
| Duration | Single-dose pharmacokinetic periods, plasma sampling over 6 hours |
| Endpoints | Total and free plasma hydroxyproline; Pro-Hyp and Hyp-Gly plasma uptake; Source/molecular-weight differences |
What the study showed, in plain terms
Key findings
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