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Effects of chronic betaine supplementation on performance in professional young soccer players during a competitive season: a double blind, randomized, placebo-controlled trial

Hadi Nobari, Jason M Cholewa, Alfonso Castillo-Rodríguez, Mehdi Kargarfard, Jorge Pérez-Gómez
Journal of the International Society of Sports Nutrition 2021 18(1):67

Bibliography

PubMed
PMID 34663363
PubMed Central
PMC8525016
DOI
10.1186/s12970-021-00464-y
Funding
Funding was not specified in the indexed record or accessible funding metadata.
Competing interests
Reported disclosure: The authors declare that they have no competing interests.

Study snapshot

DesignRandomized controlled trial
ModelHuman participants
Sample29 professional youth soccer players
InterventionBetaine 2 g/day versus placebo alongside team training
Duration14 weeks
EndpointsStrength; Sprint performance; Jump performance; Aerobic fitness

What the study showed, in plain terms

Published in 2021, this source examined exercise performance and body composition. Design: Randomized controlled trial. Sample/model: 29 professional youth soccer players. The exposure or intervention was Betaine 2 g/day versus placebo alongside team training. Follow-up or treatment period: 14 weeks.

Several strength, sprint, jump and estimated aerobic-performance measures favored betaine over the season.

Small adolescent cohort with many outcomes; linked reports share participants and should not be counted as independent replication. Companion papers describe the same 29-player soccer cohort.

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Key findings

  • Several strength, sprint, jump and estimated aerobic-performance measures favored betaine over the season.
  • The recorded outcome domains were Strength; Sprint performance; Jump performance; Aerobic fitness.
  • The result applies to the tested exposure: Betaine 2 g/day versus placebo alongside team training; 14 weeks.

What this study can and cannot tell us

  • Small adolescent cohort with many outcomes; linked reports share participants and should not be counted as independent replication. Companion papers describe the same 29-player soccer cohort.
  • An individual controlled trial must be interpreted alongside its comparator, sample size, endpoint selection and independent replication. It does not validate a different commercial formulation or a general longevity claim.
  • Source basis: Accessible full-text extract plus indexed bibliographic data. Missing method details, funding information or participant denominators are not inferred.

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Dr. Khaled Mahmoud, MBBChCritical Care Medicine, Longevity Science & Editorial Direction Dr. Amr Yasser, PhDCardiometabolic, Musculoskeletal, Gut & Bioavailability Dr. Abdulla Mostafa, PhDCellular Senescence, Neurological, Mitochondrial & Brain-Ageing Biology