Tier 2 — strong

Bioavailability of the dietary antioxidant flavonol quercetin in man

P C Hollman, J M van Trijp, M J Mengelers, J H de Vries, M B Katan
Cancer letters 1997 114(1-2):139-40

Bibliography

PubMed
PMID 9103273
DOI
10.1016/s0304-3835(97)04644-2
Funding
Funding was not specified in the indexed record or the disclosure metadata available for this entry.
Competing interests
A competing-interest declaration was not available in the indexed record or the disclosure metadata used for this entry.

Study snapshot

DesignHuman bioavailability synthesis describing dietary absorption experiments
ModelNarrative or mixed evidence review
SampleIleostomy volunteers and adults with an intact colon; sample counts not stated in the abstract
InterventionOnion glucosides, apple preparations, rutin, and quercetin aglycone
DurationAcute dietary absorption comparisons
EndpointsExposure and pharmacokinetics

What the study showed, in plain terms

Published in 1997, this source examined forms, absorption and food sources. Its evidence base was Ileostomy volunteers and adults with an intact colon; sample counts not stated in the abstract. It evaluated Onion glucosides, apple preparations, rutin, and quercetin aglycone across Acute dietary absorption comparisons.

Absorption and timing differed across glycosides and foods; onion-derived glucosides were absorbed more readily than rutin in the reported experiments.

Some results summarize earlier absorption work. This report should not automatically be counted as a separate independent intervention cohort.

Continue with Quercetin Data Center

For topic-level interpretation, read Quercetin Forms: Dihydrate, Phytosome, Liposomal and Glycosides. This is a related guide; the citation panel separately identifies articles that directly cite this paper.

Key findings

  • Absorption and timing differed across glycosides and foods; onion-derived glucosides were absorbed more readily than rutin in the reported experiments.
  • The recorded outcome domains were Exposure and pharmacokinetics.

What this study can and cannot tell us

  • Some results summarize earlier absorption work. This report should not automatically be counted as a separate independent intervention cohort.
  • The conclusions inherit the limitations of the underlying studies. A narrative interpretation or guideline recommendation is not a new randomized treatment comparison.
  • Source basis: Source check: PubMed abstract and indexed metadata; full methods were not independently confirmed for this entry. Missing method details, funding information or participant denominators are not inferred.

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Editorial review

Reviewed by the Biohack Blueprint research team

Last verified

Dr. Khaled Mahmoud, MBBChCritical Care Medicine, Longevity Science & Editorial Direction Dr. Amr Yasser, PhDCardiometabolic, Musculoskeletal, Gut & Bioavailability Dr. Abdulla Mostafa, PhDCellular Senescence, Neurological, Mitochondrial & Brain-Ageing Biology