Tier 2 — strong

One-week quercetin intervention modifies motor unit recruitment patterns before and during resistance exercise in older adults: A randomized controlled trial

Taichi Nishikawa, Tetsuya Hirono, Ryosuke Takeda, Masamichi Okudaira, Toshiyuki Ohya, Kohei Watanabe
Physiology & behavior 2024 282:114585

Bibliography

PubMed
PMID 38762195
DOI
10.1016/j.physbeh.2024.114585
Funding
Funding was not specified in the indexed record or the disclosure metadata available for this entry.
Competing interests
A competing-interest declaration was not available in the indexed record or the disclosure metadata used for this entry.

Study snapshot

DesignRandomized controlled mechanistic trial
ModelHuman intervention research
Sample24 older adults
InterventionQuercetin glycosides versus placebo; amount not stated in abstract
Duration7 days
EndpointsSource-specific outcomes described in the key findings

What the study showed, in plain terms

Published in 2024, this source examined exercise and recovery. Design: Randomized controlled mechanistic trial. Sample/model: 24 older adults. The exposure or intervention was Quercetin glycosides versus placebo; amount not stated in abstract. Follow-up or treatment period: 7 days.

Quercetin lowered motor-unit recruitment thresholds and changed firing patterns during exercise. Electrically elicited contraction did not differ between groups.

Short physiological study, with no established improvement in long-term strength or daily function.

Continue with Quercetin Data Center

For topic-level interpretation, read Quercetin for Exercise: Performance, Recovery and Muscle. This is a related guide; the citation panel separately identifies articles that directly cite this paper.

Key findings

  • Quercetin lowered motor-unit recruitment thresholds and changed firing patterns during exercise.
  • Electrically elicited contraction did not differ between groups.
  • The recorded outcome domains were Source-specific outcomes described in the key findings.
  • The result applies to the tested exposure: Quercetin glycosides versus placebo; amount not stated in abstract; 7 days.

What this study can and cannot tell us

  • Short physiological study, with no established improvement in long-term strength or daily function.
  • An individual controlled trial must be interpreted alongside its comparator, sample size, endpoint selection and independent replication. It does not validate a different commercial formulation or a general longevity claim.
  • Source basis: Source check: PubMed abstract and indexed metadata; full methods were not independently confirmed for this entry. Missing method details, funding information or participant denominators are not inferred.

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Quercetin ingestion alters motor unit behavior and enhances improvement in muscle strength following resistance training in older adults: a randomized, double-blind, controlled trial
Taichi Nishikawa et al. · European journal of nutrition · 2025

Editorial review

Reviewed by the Biohack Blueprint research team

Last verified

Dr. Khaled Mahmoud, MBBChCritical Care Medicine, Longevity Science & Editorial Direction Dr. Amr Yasser, PhDCardiometabolic, Musculoskeletal, Gut & Bioavailability Dr. Abdulla Mostafa, PhDCellular Senescence, Neurological, Mitochondrial & Brain-Ageing Biology