Tier 2 — strong

Effects of 7-day quercetin intervention on motor unit activity and muscle contractile properties before and after resistance exercise in young adults randomized controlled trials

Taichi Nishikawa, Tetsuya Hirono, Ryosuke Takeda, Masamichi Okudaira, Toshiyuki Ohya, Kohei Watanabe
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2024 49(4):447-458

Bibliography

PubMed
PMID 38033306
DOI
10.1139/apnm-2023-0208
Funding
Funding was not specified in the indexed record or the disclosure metadata available for this entry.
Competing interests
Reported disclosure: No conflicts of interest, financial or otherwise, are declared by the authors

Study snapshot

DesignRandomized controlled mechanistic trial
ModelHuman intervention research
Sample20 young adults
InterventionQuercetin glycosides 200 mg/day or placebo
Duration7 days
EndpointsSource-specific outcomes described in the key findings

What the study showed, in plain terms

Published in 2024, this source examined exercise and recovery. Design: Randomized controlled mechanistic trial. Sample/model: 20 young adults. The exposure or intervention was Quercetin glycosides 200 mg/day or placebo. Follow-up or treatment period: 7 days.

Quercetin changed motor-unit recruitment and the firing response to an exercise session.

Short study of neuromuscular physiology. It does not establish greater muscle growth, durable strength or clinical recovery.

Continue with Quercetin Data Center

For topic-level interpretation, read Quercetin for Exercise: Performance, Recovery and Muscle. This is a related guide; the citation panel separately identifies articles that directly cite this paper.

Key findings

  • Quercetin changed motor-unit recruitment and the firing response to an exercise session.
  • The recorded outcome domains were Source-specific outcomes described in the key findings.
  • The result applies to the tested exposure: Quercetin glycosides 200 mg/day or placebo; 7 days.

What this study can and cannot tell us

  • Short study of neuromuscular physiology. It does not establish greater muscle growth, durable strength or clinical recovery.
  • An individual controlled trial must be interpreted alongside its comparator, sample size, endpoint selection and independent replication. It does not validate a different commercial formulation or a general longevity claim.
  • Source basis: Source check: PubMed abstract and indexed metadata; full methods were not independently confirmed for this entry. Missing method details, funding information or participant denominators are not inferred.

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Jennifer A Kurtz et al. · Nutrients · 2025
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Quercetin ingestion alters motor unit behavior and enhances improvement in muscle strength following resistance training in older adults: a randomized, double-blind, controlled trial
Taichi Nishikawa et al. · European journal of nutrition · 2025

Editorial review

Reviewed by the Biohack Blueprint research team

Last verified

Dr. Khaled Mahmoud, MBBChCritical Care Medicine, Longevity Science & Editorial Direction Dr. Amr Yasser, PhDCardiometabolic, Musculoskeletal, Gut & Bioavailability Dr. Abdulla Mostafa, PhDCellular Senescence, Neurological, Mitochondrial & Brain-Ageing Biology