Tier 2 — strong

Quercetin Supplementation Improves Neuromuscular Function Recovery from Muscle Damage

Ilenia Bazzucchi, Federica Patrizio, Roberta Ceci, Guglielmo Duranti, Stefania Sabatini, Paolo Sgrò, Luigi Di Luigi, Massimo Sacchetti
Nutrients 2020 12(9):2850

Bibliography

PubMed
PMID 32957571
PubMed Central
PMC7551500
DOI
10.3390/nu12092850
Funding
Funding was not specified in the indexed record or the disclosure metadata available for this entry.
Competing interests
Reported disclosure: The authors declare no conflict of interest.

Study snapshot

DesignDouble-blind crossover exercise study
ModelHuman intervention research
Sample16 young men
InterventionQuercetin 1,000 mg/day versus placebo
Duration14 days supplementation; 7-day post-exercise follow-up
EndpointsExercise performance or recovery

What the study showed, in plain terms

Published in 2020, this source examined exercise and recovery. Design: Double-blind crossover exercise study. Sample/model: 16 young men. The exposure or intervention was Quercetin 1,000 mg/day versus placebo. Follow-up or treatment period: 14 days supplementation; 7-day post-exercise follow-up.

Quercetin attenuated post-exercise strength loss and several muscle-damage measures.

Small study of experimentally induced eccentric damage. Results do not establish better everyday training outcomes or long-term muscle preservation.

Continue with Quercetin Data Center

For topic-level interpretation, read Quercetin for Exercise: Performance, Recovery and Muscle. This is a related guide; the citation panel separately identifies articles that directly cite this paper.

Key findings

  • Quercetin attenuated post-exercise strength loss and several muscle-damage measures.
  • The recorded outcome domains were Exercise performance or recovery.
  • The result applies to the tested exposure: Quercetin 1,000 mg/day versus placebo; 14 days supplementation; 7-day post-exercise follow-up.

What this study can and cannot tell us

  • Small study of experimentally induced eccentric damage. Results do not establish better everyday training outcomes or long-term muscle preservation.
  • An individual controlled trial must be interpreted alongside its comparator, sample size, endpoint selection and independent replication. It does not validate a different commercial formulation or a general longevity claim.
  • Source basis: Source check: accessible full text and indexed metadata. Missing method details, funding information or participant denominators are not inferred.

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Editorial review

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Dr. Khaled Mahmoud, MBBChCritical Care Medicine, Longevity Science & Editorial Direction Dr. Amr Yasser, PhDCardiometabolic, Musculoskeletal, Gut & Bioavailability Dr. Abdulla Mostafa, PhDCellular Senescence, Neurological, Mitochondrial & Brain-Ageing Biology