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The Effects of Quercetin Supplementation on Eccentric Exercise-Induced Muscle Damage

Ilenia Bazzucchi, Federica Patrizio, Roberta Ceci, Guglielmo Duranti, Paolo Sgrò, Stefania Sabatini, Luigi Di Luigi, Massimo Sacchetti, Francesco Felici
Nutrients 2019 11(1):205

Bibliography

PubMed
PMID 30669587
PubMed Central
PMC6356612
DOI
10.3390/nu11010205
Funding
Funding was not specified in the indexed record or the disclosure metadata available for this entry.
Competing interests
Reported disclosure: The authors declare no conflict of interest.

Study snapshot

DesignRandomized double-blind crossover exercise trial
ModelHuman intervention research
Sample12 young men
InterventionQuercetin 1,000 mg/day versus placebo
Duration14 days before an eccentric-exercise challenge
EndpointsSource-specific outcomes described in the key findings

What the study showed, in plain terms

Published in 2019, this source examined exercise and recovery. Design: Randomized double-blind crossover exercise trial. Sample/model: 12 young men. The exposure or intervention was Quercetin 1,000 mg/day versus placebo. Follow-up or treatment period: 14 days before an eccentric-exercise challenge.

Quercetin attenuated immediate weakness and neuromuscular impairment after the damaging exercise protocol.

Small laboratory exercise trial in men. It does not establish chronic hypertrophy or improved sports performance.

Continue with Quercetin Data Center

For topic-level interpretation, read Quercetin for Exercise: Performance, Recovery and Muscle. This is a related guide; the citation panel separately identifies articles that directly cite this paper.

Key findings

  • Quercetin attenuated immediate weakness and neuromuscular impairment after the damaging exercise protocol.
  • The recorded outcome domains were Source-specific outcomes described in the key findings.
  • The result applies to the tested exposure: Quercetin 1,000 mg/day versus placebo; 14 days before an eccentric-exercise challenge.

What this study can and cannot tell us

  • Small laboratory exercise trial in men. It does not establish chronic hypertrophy or improved sports performance.
  • An individual controlled trial must be interpreted alongside its comparator, sample size, endpoint selection and independent replication. It does not validate a different commercial formulation or a general longevity claim.
  • Source basis: Source check: accessible full text and indexed metadata. Missing method details, funding information or participant denominators are not inferred.

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Editorial review

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Dr. Khaled Mahmoud, MBBChCritical Care Medicine, Longevity Science & Editorial Direction Dr. Amr Yasser, PhDCardiometabolic, Musculoskeletal, Gut & Bioavailability Dr. Abdulla Mostafa, PhDCellular Senescence, Neurological, Mitochondrial & Brain-Ageing Biology