Tier 2 — strong

Chronic consumption of quercetin reduces erythrocytes oxidative damage: Evaluation at resting and after eccentric exercise in humans

Guglielmo Duranti, Roberta Ceci, Federica Patrizio, Paolo Sgrò, Luigi Di Luigi, Stefania Sabatini, Francesco Felici, Ilenia Bazzucchi
Nutrition research (New York, N.Y.) 2018 50:73

Bibliography

PubMed
PMID 29540274
DOI
10.1016/j.nutres.2017.12.002
Funding
Funding was not specified in the indexed record or the disclosure metadata available for this entry.
Competing interests
A competing-interest declaration was not available in the indexed record or the disclosure metadata used for this entry.

Study snapshot

DesignRandomized controlled crossover exercise study
ModelHuman intervention research
Sample14 participants
InterventionQuercetin 1,000 mg/day versus placebo
Duration2 weeks
EndpointsLipid measurements; Oxidative-stress measures; Protein activity, binding or signaling

What the study showed, in plain terms

Published in 2018, this source examined exercise and recovery. Design: Randomized controlled crossover exercise study. Sample/model: 14 participants. The exposure or intervention was Quercetin 1,000 mg/day versus placebo. Follow-up or treatment period: 2 weeks.

Red-cell lipid-peroxidation and hemolysis-susceptibility measures improved, while resting antioxidant-enzyme and glutathione measures did not.

Laboratory redox endpoints after an experimental exercise challenge. Clinical benefit and long-term safety were not established.

Continue with Quercetin Data Center

For topic-level interpretation, read Quercetin for Exercise: Performance, Recovery and Muscle. This is a related guide; the citation panel separately identifies articles that directly cite this paper.

Key findings

  • Red-cell lipid-peroxidation and hemolysis-susceptibility measures improved, while resting antioxidant-enzyme and glutathione measures did not.
  • The recorded outcome domains were Lipid measurements; Oxidative-stress measures; Protein activity, binding or signaling.
  • The result applies to the tested exposure: Quercetin 1,000 mg/day versus placebo; 2 weeks.

What this study can and cannot tell us

  • Laboratory redox endpoints after an experimental exercise challenge. Clinical benefit and long-term safety were not established.
  • An individual controlled trial must be interpreted alongside its comparator, sample size, endpoint selection and independent replication. It does not validate a different commercial formulation or a general longevity claim.
  • Source basis: Source check: PubMed abstract and indexed metadata; full methods were not independently confirmed for this entry. Missing method details, funding information or participant denominators are not inferred.

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Editorial review

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Dr. Khaled Mahmoud, MBBChCritical Care Medicine, Longevity Science & Editorial Direction Dr. Amr Yasser, PhDCardiometabolic, Musculoskeletal, Gut & Bioavailability Dr. Abdulla Mostafa, PhDCellular Senescence, Neurological, Mitochondrial & Brain-Ageing Biology