Tier 1 — highest

Effects of supplementation with quercetin on plasma C-reactive protein concentrations: a systematic review and meta-analysis of randomized controlled trials

M Mohammadi-Sartang, Z Mazloom, S Sherafatmanesh, M Ghorbani, Donya Firoozi
European journal of clinical nutrition 2017 71(9):1033

Bibliography

PubMed
PMID 28537580
DOI
10.1038/ejcn.2017.55
Funding
Funding was not specified in the indexed record or the disclosure metadata available for this entry.
Competing interests
A competing-interest declaration was not available in the indexed record or the disclosure metadata used for this entry.

Study snapshot

DesignSystematic review and meta-analysis of randomized trials
ModelHuman evidence synthesis
Sample7 trials; 10 treatment arms
InterventionQuercetin supplementation
DurationSearches through June 16, 2016
EndpointsInflammatory measures

What the study showed, in plain terms

Published in 2017, this source examined immunity and respiratory health. Its evidence base was 7 trials; 10 treatment arms. It evaluated Quercetin supplementation across Searches through June 16, 2016.

Circulating CRP decreased modestly in the pooled analysis.

CRP is a surrogate marker, and included populations and regimens varied. The result does not establish improved symptoms or disease prevention.

Continue with Quercetin Data Center

For topic-level interpretation, read Quercetin for Inflammation: CRP, Pain and Human Trials. This is a related guide; the citation panel separately identifies articles that directly cite this paper.

Key findings

  • Circulating CRP decreased modestly in the pooled analysis.
  • The recorded outcome domains were Inflammatory measures.
  • This synthesis reuses the included study populations; it is not an additional randomized participant cohort.

What this study can and cannot tell us

  • CRP is a surrogate marker, and included populations and regimens varied. The result does not establish improved symptoms or disease prevention.
  • Pooled estimates depend on the included trials and may share participants with companion publications or other reviews. A statistically significant surrogate outcome does not establish disease prevention.
  • Source basis: Source check: PubMed abstract and indexed metadata; full methods were not independently confirmed for this entry. Missing method details, funding information or participant denominators are not inferred.

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Impact of quercetin on systemic levels of inflammation: a meta-analysis of randomised controlled human trials
Qiaowen Ou et al. · International journal of food sciences and nutrition · 2020

Citation network

Articles citing this research paper

2 articles

Biohack Blueprint analyses that reference this study in their evidence base.

Editorial review

Reviewed by the Biohack Blueprint research team

Last verified

Dr. Khaled Mahmoud, MBBChCritical Care Medicine, Longevity Science & Editorial Direction Dr. Amr Yasser, PhDCardiometabolic, Musculoskeletal, Gut & Bioavailability Dr. Abdulla Mostafa, PhDCellular Senescence, Neurological, Mitochondrial & Brain-Ageing Biology