Tier 1 — highest

Magnesium supplementation improves indicators of low magnesium status and inflammatory stress in adults older than 51 years with poor quality sleep

Forrest H Nielsen, LuAnn K Johnson, Huawei Zeng
Magnesium research 2010 23(4):158-68

Bibliography

PubMed
PMID 21199787
DOI
10.1684/mrh.2010.0220
Funding
Funding is not specified in the indexed abstract or accessible funding metadata. Consult the original publication for the declaration.
Competing interests
A competing-interest declaration is not available in the indexed abstract or accessible disclosure metadata.

Study snapshot

DesignRandomized controlled clinical trial
ModelHuman participants
Sample100 adults over 51 randomized; 96 completed
Intervention320 mg/day elemental magnesium as citrate or placebo
Duration7 weeks
EndpointsSleep quality; Magnesium status; C-reactive protein

What the study showed, in plain terms

This publication examines sleep quality, magnesium status, c-reactive protein. Study population or evidence base: 100 adults over 51 randomized; 96 completed. Intervention or exposure: 320 mg/day elemental magnesium as citrate or placebo.

Key findings

Sleep scores improved in both groups. Magnesium improved selected status and inflammation measures in participants with low magnesium or elevated CRP at baseline.

What this study can and cannot tell us

No clear magnesium-specific sleep benefit was demonstrated. Subgroup biomarker changes should not be presented as proof of insomnia treatment.

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