Tier 1 — highest

The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial

Behnood Abbasi, Masud Kimiagar, Khosro Sadeghniiat, Minoo M Shirazi, Mehdi Hedayati, Bahram Rashidkhani
Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 2012 17(12):1161-9

Bibliography

PubMed
PMID 23853635
PubMed Central
PMC3703169
Funding
Funding or support is described in the linked original publication; the indexed record does not provide a concise sponsor attribution.
Competing interests
The authors report no relevant competing interests.

Study snapshot

DesignRandomized, double-blind, placebo-controlled clinical trial
ModelHuman participants
Sample46 older adults with primary insomnia
Intervention500 mg/day magnesium or placebo, as reported in the study
Duration8 weeks
EndpointsInsomnia severity; Sleep efficiency and latency; Melatonin and cortisol

What the study showed, in plain terms

This publication examines insomnia severity, sleep efficiency and latency, melatonin and cortisol. Study population or evidence base: 46 older adults with primary insomnia. Intervention or exposure: 500 mg/day magnesium or placebo, as reported in the study.

Key findings

Selected subjective insomnia measures and hormonal markers improved with magnesium. Total sleep time did not significantly differ between groups.

What this study can and cannot tell us

Small trial with predominantly subjective sleep outcomes. Hormonal changes are not equivalent to objective sleep-stage measurements.

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