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Specific Dietary (Poly)phenols Are Associated with Sleep Quality in a Cohort of Italian Adults

Justyna Godos, Raffaele Ferri, Sabrina Castellano, Donato Angelino, Pedro Mena, Daniele Del Rio, Filippo Caraci, Fabio Galvano, Giuseppe Grosso
Nutrients 2020 12(5):1226

Bibliography

PubMed
PMID 32357534
PubMed Central
PMC7282005
DOI
10.3390/nu12051226
Funding
Partially supported by the Italian Ministry of Health “Ricerca Corrente” (RC n. 2751594).
Competing interests
The authors declared no conflict of interest.

Study snapshot

DesignCross-sectional observational analysis within an Italian adult cohort
ModelAdults living in southern Italy
Sample1,936 adults
InterventionNo assigned intervention; habitual dietary polyphenol intake estimated from FFQs and Phenol-Explorer data
DurationCross-sectional dietary and sleep assessment
EndpointsPittsburgh Sleep Quality Index; Estimated dietary apigenin intake; Estimated polyphenol intake; Odds of inadequate sleep quality; Weight-status subgroup associations

What the study showed, in plain terms

This study examined whether habitual dietary intake of specific polyphenols, including apigenin, was associated with sleep quality in 1,936 Italian adults.

Key findings

Dietary apigenin intake was among the individual flavonoids associated with sleep-quality measures. Associations were stronger for several polyphenols in normal-weight participants, while the overweight/obese subgroup did not show associations for polyphenol classes. The study supports an observational signal, not proof that apigenin supplementation improves sleep.

What this study can and cannot tell us

Dietary exposure was estimated from food-frequency questionnaires and databases rather than assigned or directly measured. The cross-sectional design cannot prove causality, residual confounding is possible, and dietary apigenin is not equivalent to an isolated apigenin supplement.

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Dr. Khaled Mahmoud, MBBChCritical Care Medicine, Longevity Science & Editorial Direction Dr. Amr Yasser, PhDCardiometabolic, Musculoskeletal, Gut & Bioavailability Dr. Abdulla Mostafa, PhDCellular Senescence, Neurological, Mitochondrial & Brain-Ageing Biology