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Bioavailability and inter-conversion of sulforaphane and erucin in human subjects consuming broccoli sprouts or broccoli supplement in a cross-over study design
Pharmacological Research
2011
64(5):456-463
Bibliography
- PubMed
- PMID 21816223
- PubMed Central
- PMC3183106
- Funding
- Supported by NIH grants CA090890 and CA122906, Oregon AES OR00735, and NIEHS P30 ES00210.
Study snapshot
| Design | Human crossover bioavailability study |
|---|---|
| Model | Healthy adults |
| Sample | 16 |
| Intervention | Twelve subjects consumed 40 g fresh broccoli sprouts and, after a one-month washout, six broccoli-supplement pills; four additional control subjects received alfalfa sprouts and placebo pills. |
| Duration | Two 48-hour sampling phases separated by one month |
| Endpoints | Plasma sulforaphane metabolites; Urinary sulforaphane metabolites; Erucin metabolites; Bioavailability; Interconversion of sulforaphane and erucin |
What the study showed, in plain terms
Key findings
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