Tier 2 — strong
Berberine containing quadruple therapy for initial Helicobacter pylori eradication: An open-label randomized phase IV trial
Medicine
2017
96(32):e7697
Bibliography
- PubMed
- PMID 28796053
- PubMed Central
- PMC5556219
- Funding
- Funding was not established from the accessible source; this is not a declaration of no funding.
- Competing interests
- A complete competing-interest declaration was not available in the accessible source; no absence of conflicts is inferred.
Study snapshot
| Design | Open-label phase IV randomized noninferiority trial |
|---|---|
| Model | Human participants; see population |
| Sample | 612 treatment-naive patients |
| Intervention | Berberine-containing quadruple regimen versus bismuth-containing quadruple regimen |
| Duration | 14 days; eradication test 28 days later |
| Endpoints | Eradication or stool-output outcomes; Treatment tolerability; Adherence |
What the study showed, in plain terms
Key findings
What this study can and cannot tell us
Editorial review
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