Tier 1 — highest
A randomized, double-blind, placebo-controlled trial of oral Matricaria recutita (chamomile) extract therapy for generalized anxiety disorder
Journal of Clinical Psychopharmacology
2009
29(4):378-382
Bibliography
- PubMed
- PMID 19593179
- PubMed Central
- PMC3600416
Study snapshot
| Design | Randomized double-blind placebo-controlled trial |
|---|---|
| Model | Adults with mild-to-moderate generalized anxiety disorder |
| Sample | |
| Intervention | Oral Matricaria recutita chamomile extract versus placebo |
| Duration | 8 weeks |
| Endpoints | Hamilton Anxiety Rating Scale; Clinical response; Safety and tolerability |
What the study showed, in plain terms
Key findings
What this study can and cannot tell us
Citation network
Articles citing this research paper
Biohack Blueprint analyses that reference this study in their evidence base.
- Apigenin for Anxiety and Relaxation: What Does the Evidence Show?Does apigenin help anxiety? A 2026 evidence review of GABA mechanisms, chamomile trials, preclinical systematic-review data, dose, timing, medications and relaxation stacks.Read analysis
- Apigenin in Chamomile: How Much Is There and Does Chamomile Help Sleep?How much apigenin is in chamomile? A practical guide to tea, flowers, human absorption, sleep and anxiety evidence, cup-to-capsule comparisons and timing.Read analysis
Editorial review
Reviewed by the Biohack Blueprint research team
Last verified



