Tier 3 — preclinical
Effect of a Daily Collagen Peptide Supplement on Digestive Symptoms in Healthy Women: 2-Phase Mixed Methods Study
JMIR Formative Research
2022
6(5):e36339
Bibliography
- PubMed
- PMID 35639457
- PubMed Central
- PMC9198822
- DOI
- 10.2196/36339
- Trial registry
- View on ClinicalTrials.gov Registered trial — results not yet published in a peer-reviewed journal.
- Funding
- Research industry links: one coauthor employed by collagen manufacturer Rousselot.
- Competing interests
- Janne Prawitt employed by Rousselot BV; formulation is Peptan.
Study snapshot
| Design | Prospective open-label single-arm digital feasibility pilot following exploratory qualitative phase |
|---|---|
| Model | Otherwise healthy women with BMI >25 kg/m² and self-reported digestive symptoms |
| Sample | 40 enrolled; 14 (35%) completed full 8-week supplementation |
| Intervention | 20 g/day Peptan collagen peptides (two divided doses); no concurrent placebo control |
| Duration | 2-week symptom baseline plus 8-week intervention |
| Endpoints | Self-reported bloating and digestive symptoms; Adherence; Study feasibility |
What the study showed, in plain terms
Key findings
What this study can and cannot tell us
Citation network
Articles citing this research paper
Biohack Blueprint analyses that reference this study in their evidence base.
- Collagen Peptides Benefits: Do Hydrolysed Collagen Peptides Work?Evidence varies by outcome: possible modest skin benefits, formulation-specific joint and bone signals, weaker direct muscle-building evidence, and limited hair, nail and...Read analysis
- Hydrolysed Collagen Peptides: Benefits, Dosage, Safety & EvidenceA complete evidence-graded guide to hydrolysed collagen peptides: what human studies suggest for skin, joints and bone, where evidence is uncertain, plus...Read analysis
- Collagen for Gut Health: What Human Studies ShowHuman evidence for collagen and gut health is preliminary, with no controlled evidence that it repairs the gut barrier. Here’s what the...Read analysis
Editorial review
Reviewed by the Biohack Blueprint research team
Last verified
