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Influence of collagen peptide supplementation on visible signs of skin and nail health and -aging in an East Asian population: A double blind, randomized, placebo-controlled trial

Sara Vleminckx, Nicolina Virgilio, Jerome Asserin, Janne Prawitt, Catarina I. F. Silva

Journal of Cosmetic Dermatology 2024 23(11):3645-3653

Bibliography

PubMed: PMID 39143887
DOI: 10.1111/jocd.16458
Funding: Rousselot BV provided funding and test products for the study.
Competing interests: Vleminckx, Virgilio, Silva and Prawitt were employees of Rousselot BV; Asserin was an employee of COSderma Laboratories.

Study snapshot

Design	Double-blind, randomized, placebo-controlled trial
Model	Healthy East Asian women aged 43–65 years
Sample	85
Intervention	5 g/day collagen peptide supplement versus 5 g/day maltodextrin placebo, with standardized facial skincare in both groups.
Duration	84 days
Endpoints	Dermis density; Skin moisture; Skin elasticity; Wrinkle visibility; Beauty perception; Nail color

What the study showed, in plain terms

Eighty-five healthy women were randomized to 5 g/day collagen peptides or maltodextrin for 84 days while using standardized skincare. Some instrumental skin measures favored collagen, but the trial was funded by Rousselot and most authors worked for the manufacturer.

Key findings

At day 84, dermis density and skin moisture were reported as significantly better in the collagen group versus placebo. Several other measures improved earlier within the collagen group, although within-group timing differences are less informative than direct between-group comparisons.

What this study can and cannot tell us

Manufacturer-funded with four of five authors employed by Rousselot; limited to women aged 43–65 in an East Asian population; a standardized facial cream was used in both arms; multiple outcomes increase the importance of prespecified analyses and multiplicity control.

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Jul 8, 2026 Collagen for Hair Growth & Nails: What Evidence ShowsNail evidence comes largely from a small uncontrolled study, while direct hair-growth evidence is weaker. Here’s what can—and cannot—be concluded.Read analysis

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