Tier 1 — highest
Oral sulforaphane increases Phase II antioxidant enzymes in the human upper airway
Clinical Immunology
2009
130(3):244-251
Bibliography
- PubMed
- PMID 19028145
- PubMed Central
- PMC2668525
- Funding
- Supported by NIH/NCRR K12 R011 7611, NIH/NIAID P01 AI050495, NIEHS 5P01ES09581-10, and U.S. EPA grant RD83186101.
Study snapshot
| Design | Single-blind placebo-controlled dose-escalation trial |
|---|---|
| Model | Healthy adults |
| Sample | 65 |
| Intervention | Standardized broccoli sprout homogenate prepared from 25 to 200 g broccoli sprouts daily for three days; 200 g alfalfa sprout homogenate served as control |
| Duration | 3 days |
| Endpoints | Nasal-lavage GSTM1 expression; GSTP1 expression; NQO1 expression; HO-1 expression; Tolerability |
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