Tier 3 — preclinical
Quercetin as a modulator of xenobiotic metabolism: integrating CYP450 regulation, phase II conjugation pathways, and transporter-mediated drug interactions
European journal of clinical pharmacology
2026
82(11):263
Bibliography
- PubMed
- PMID 42827146
- Funding
- Funding was not specified in the indexed record or the disclosure metadata available for this entry.
- Competing interests
- Reported disclosure: Declarations. Ethics and consent to participate: Not applicable. This manuscript is a review of previously published literature and does not involve original studies with human participants, human tissues, identifiable personal data, or animals conducted by the authors. Therefore, ethics committee approval and informed consent to participate were not required. Consent for publication: Not applicable. Competing interests: The authors declare that they have no competing financial or non-financial interests.
Study snapshot
| Design | Systematic review of human and mechanistic drug-metabolism evidence |
|---|---|
| Model | Mixed human and preclinical evidence synthesis |
| Sample | Clinical pharmacokinetic and laboratory studies; no new participant cohort |
| Intervention | Quercetin effects on CYP enzymes, conjugation pathways, and drug transporters |
| Duration | Literature available at publication in 2026 |
| Endpoints | Exposure and pharmacokinetics |
What the study showed, in plain terms
Key findings
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