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Clinical effectiveness of quercetin supplementation in the management of weight loss: a pooled analysis of randomized controlled trials

Haohai Huang, Dan Liao, Yong Dong, Rong Pu
Diabetes, metabolic syndrome and obesity : targets and therapy 2019 12:553-563

Bibliography

PubMed
PMID 31114281
PubMed Central
PMC6497115
DOI
10.2147/DMSO.S199830
Funding
Funding was not specified in the indexed record or the disclosure metadata available for this entry.
Competing interests
Reported disclosure: The authors report no conflicts of interest in this work.

Study snapshot

DesignSystematic review and meta-analysis of randomized trials
ModelHuman evidence synthesis
Sample9 trials, 11 treatment arms, 525 participants
InterventionQuercetin supplementation versus comparison conditions
DurationIncluded trial durations varied
EndpointsSource-specific outcomes described in the key findings

What the study showed, in plain terms

Published in 2019, this source examined evidence reviews and human mechanisms. Its evidence base was 9 trials, 11 treatment arms, 525 participants. It evaluated Quercetin supplementation versus comparison conditions across Included trial durations varied.

Pooled analyses did not show significant reductions in body weight, BMI, waist circumference or waist-to-hip ratio.

Trial heterogeneity and limited longer-term data remain. This synthesis does not support presenting quercetin as an established weight-loss supplement.

Continue with Quercetin Data Center

For topic-level interpretation, read Quercetin Benefits: What Human Studies Actually Show. This is a related guide; the citation panel separately identifies articles that directly cite this paper.

Key findings

  • Pooled analyses did not show significant reductions in body weight, BMI, waist circumference or waist-to-hip ratio.
  • The recorded outcome domains were Source-specific outcomes described in the key findings.
  • This synthesis reuses the included study populations; it is not an additional randomized participant cohort.

What this study can and cannot tell us

  • Trial heterogeneity and limited longer-term data remain. This synthesis does not support presenting quercetin as an established weight-loss supplement.
  • Pooled estimates depend on the included trials and may share participants with companion publications or other reviews. A statistically significant surrogate outcome does not establish disease prevention.
  • Source basis: Source check: accessible full text and indexed metadata. Missing method details, funding information or participant denominators are not inferred.

Editorial review

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Dr. Khaled Mahmoud, MBBChCritical Care Medicine, Longevity Science & Editorial Direction Dr. Amr Yasser, PhDCardiometabolic, Musculoskeletal, Gut & Bioavailability Dr. Abdulla Mostafa, PhDCellular Senescence, Neurological, Mitochondrial & Brain-Ageing Biology