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Exposure of breastfed infants to quercetin after consumption of a single meal rich in quercetin by their mothers

Ewa Romaszko, Wiesław Wiczkowski, Jerzy Romaszko, Joanna Honke, Mariusz K Piskula
Molecular nutrition & food research 2014 58(2):221-8

Bibliography

PubMed
PMID 23963751
DOI
10.1002/mnfr.201200773
Funding
Funding was not specified in the indexed record or the disclosure metadata available for this entry.
Competing interests
A competing-interest declaration was not available in the indexed record or the disclosure metadata used for this entry.

Study snapshot

DesignControlled maternal dietary-exposure study
ModelHuman intervention research
Sample11 breastfeeding women
InterventionSingle meal providing quercetin 1 mg/kg during a restricted diet
Duration5-day observation with milk and urine sampling
EndpointsExposure and pharmacokinetics

What the study showed, in plain terms

Published in 2014, this source examined safety, interactions and special populations. Design: Controlled maternal dietary-exposure study. Sample/model: 11 breastfeeding women. The exposure or intervention was Single meal providing quercetin 1 mg/kg during a restricted diet. Follow-up or treatment period: 5-day observation with milk and urine sampling.

Quercetin concentrations in milk increased after the meal, demonstrating transfer from maternal dietary intake.

Dietary exposure study, not a supplement-safety trial in mothers or infants. It does not establish safety of high-dose quercetin while breastfeeding.

Continue with Quercetin Data Center

For topic-level interpretation, read Quercetin Side Effects and Safety: A Practical Guide. This is a related guide; the citation panel separately identifies articles that directly cite this paper.

Key findings

  • Quercetin concentrations in milk increased after the meal, demonstrating transfer from maternal dietary intake.
  • The recorded outcome domains were Exposure and pharmacokinetics.
  • The result applies to the tested exposure: Single meal providing quercetin 1 mg/kg during a restricted diet; 5-day observation with milk and urine sampling.

What this study can and cannot tell us

  • Dietary exposure study, not a supplement-safety trial in mothers or infants. It does not establish safety of high-dose quercetin while breastfeeding.
  • An individual controlled trial must be interpreted alongside its comparator, sample size, endpoint selection and independent replication. It does not validate a different commercial formulation or a general longevity claim.
  • Source basis: Source check: PubMed abstract and indexed metadata; full methods were not independently confirmed for this entry. Missing method details, funding information or participant denominators are not inferred.

Citation network

Articles citing this research paper

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Dr. Khaled Mahmoud, MBBChCritical Care Medicine, Longevity Science & Editorial Direction Dr. Amr Yasser, PhDCardiometabolic, Musculoskeletal, Gut & Bioavailability Dr. Abdulla Mostafa, PhDCellular Senescence, Neurological, Mitochondrial & Brain-Ageing Biology