Tier 3 — preclinical

Improvement in intestinal coenzyme q10 absorption by food intake

Akiko Ochiai, Shirou Itagaki, Toshimitsu Kurokawa, Masaki Kobayashi, Takeshi Hirano, Ken Iseki
Yakugaku Zasshi 2007 127(8):1251-1254

Bibliography

PubMed
PMID 17666877

Study snapshot

DesignHuman oral absorption and formulation study
ModelHuman participants
Sample
InterventionOral CoQ10 with food conditions; emulsion and suspension formulations were compared
DurationSingle-dose absorption assessment
EndpointsPeak plasma CoQ10 concentration; Extent of CoQ10 absorption; Food effect; Formulation effect

What the study showed, in plain terms

This human absorption study examined how food intake and formulation influenced oral CoQ10 exposure.

Food intake enhanced intestinal CoQ10 absorption, and an emulsion formulation produced higher peak concentration and overall absorption than a suspension formulation.

Key findings

Food intake enhanced oral CoQ10 absorption in the human study.

The emulsion formulation produced a greater peak concentration and extent of absorption than the suspension formulation.

Food also enhanced absorption of the emulsion formulation.

What this study can and cannot tell us

The PubMed abstract provides limited methodological detail, and the study focused on pharmacokinetic absorption rather than health outcomes.

It does not establish a preferred morning or nighttime dosing window.

Citation network

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