Tier 4 — mechanistic

Determination of NAD+ precursors nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) in plant foods: exploring dietary sources

Gabriela Fabiana Soares Alegre, Glaucia Maria Pastore
CyTA - Journal of Food 2025 23; 1

Bibliography

Funding
CAPES-Brazil grant 88887.353067/2019–00 and FAPESP-Brazil grant 2020/08761-4, as disclosed in the publisher repository.
Competing interests
A complete competing-interest statement was not verified from the accessible publisher materials.

Study snapshot

DesignValidated HPLC-DAD/UV analysis with LC-MS/MS confirmation
ModelCommon plant foods and non-conventional Amazon plant foods
SamplePlant-food samples; no human supplementation participants
InterventionMeasurement of NR, NMN and NAD+ in fresh-weight food samples
DurationLaboratory analytical study
EndpointsNR concentration; NMN concentration; NAD+ concentration; Analytical validation

What the study showed, in plain terms

This analytical study measured NR, NMN and NAD+ separately in plant foods rather than treating total vitamin B3 as NR.

Key findings

The publisher summary reports NR concentrations ranging from 62 to 1600 micrograms per 100 g fresh weight, with wild chicory, banana and orange among the higher-NR foods tested.

What this study can and cannot tell us

Composition varies by sample and method. Food concentration does not establish absorbed exposure or a clinical anti-aging benefit, and NMN concentrations must not be relabeled as NR. Exact food-specific numerical tables were not verified for this summary.

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