Tier 2 — strong
Evaluation of Nicotinamide Riboside in Prevention of Small Nerve Fiber Axon Degeneration and Promotion of Nerve Regeneration
Journal of the peripheral nervous system : JPNS
2026
31; 1; e70101
Bibliography
- PubMed
- PMID 41502156
- Funding
- Indexed grant support includes Dr. Miriam and Sheldon G. Adelson Medical Research Foundation. The complete funding declaration is not specified in the accessible abstract.
- Competing interests
- A complete competing-interest declaration is not specified in the accessible publication information.
Study snapshot
| Design | Randomized placebo-controlled human trial |
|---|---|
| Model | Human participants |
| Sample | Human phase II participants; denominator not established from the indexed abstract |
| Intervention | Oral synthetic NR versus placebo in an experimental capsaicin model |
| Duration | Follow-up through 90 days |
| Endpoints | Skin nerve-fiber density; degeneration and reinnervation; NAD+ |
What the study showed, in plain terms
Key findings
What this study can and cannot tell us
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